Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
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GHSR / Ghrelin Receptor
growth hormone secretagogue receptor
GHSR / Ghrelin Receptor is a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate activity of isoform 1a. Mutations in this gene are associated with autosomal idiopathic short stature.
Electroacupuncture improves acute bowel injury recovery in rat models. Wu J, Lyu B, Gan T, Wang L, Zhu M. Experimental and therapeutic medicine. 2017 14:4655-4662. (WB; Human)[Full Text Article]
Related Antibodies: LS-C136920.
Characterization of a Monoclonal Antibody Specific for the Growth Hormone Secretagogue Receptor. Crotta K, Casnici C, Tonna N, Lattuada D, Bianco F, Marelli O. Monoclonal antibodies in immunodiagnosis and immunotherapy. 2017 36:37-43. (WB; Human)[Full Text Article]