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GHRL / Ghrelin Preproprotein

Ghrelin/Obestatin Prepropeptide

GHRL / Ghrelin Preproprotein is the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression.

Gene Name: Ghrelin/Obestatin Prepropeptide
Synonyms: GHRL, Ghrelin, Growth hormone secretagogue, Motilin-related peptide, Obestatin, Appetite-regulating hormone, MTLRP, Protein M46
Target Sequences: NM_016362 NP_057446.1 Q9UBU3

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Antibodies (17)
Primary (17)
GHRL / Ghrelin Preproprotein (17)
Human (17)
Mouse (10)
Rat (12)
Dog (8)
Monkey (1)
IHC (6)
IHC-P (2)
WB (15)
ELISA (4)
ICC (8)
IP (8)
Peptide-ELISA (2)
rabbit (8)
mouse (8)
goat (1)
Product Group
IHCPlus (1)
IgG (7)
IgG2b,l (8)
monoclonal mc (8)
polyclonal pc (9)
APC (1)
APC Conjugated (1)
Biotin Conjugated (2)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Preservative Free (1)
Unconjugated (9)
aa1-117 (1)
aa103-117 (1)
No (17)
GHRL / Ghrelin Preproprotein Antibody - Anti-Ghrelin antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2 ug/ml.
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GHRL / Ghrelin Preproprotein Goat anti-Human Polyclonal (aa103-117) Antibody
Human, Monkey
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µg/$485
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GHRL / Ghrelin Preproprotein Mouse anti-Human Monoclonal Antibody
Mouse, Dog, Rat, Human
ICC, IP, WB
Unconjugated
100 µl/$317; 200 µl/$363; 500 µl/$515; 1 ml/$591; 2 ml/$816; 5 ml/$1,331
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GHRL / Ghrelin Preproprotein Mouse anti-Human Monoclonal (HRP) Antibody
Mouse, Dog, Rat, Human
ICC, IP, WB
HRP Conjugated
100 µl/$349; 200 µl/$408; 500 µl/$609; 1 ml/$762; 2 ml/$999; 5 ml/$1,729
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GHRL / Ghrelin Preproprotein Mouse anti-Human Monoclonal (Biotin) Antibody
Mouse, Dog, Rat, Human
ICC, IP, WB
Biotin Conjugated
100 µl/$328; 200 µl/$378; 500 µl/$545; 1 ml/$645; 2 ml/$879; 5 ml/$1,464
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GHRL / Ghrelin Preproprotein Mouse anti-Human Monoclonal (FITC) Antibody
Mouse, Dog, Rat, Human
ICC, IP, WB
FITC Conjugated
100 µl/$359; 200 µl/$423; 500 µl/$655; 1 ml/$816; 2 ml/$1,055; 5 ml/$1,863
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GHRL / Ghrelin Preproprotein Mouse anti-Human Monoclonal (APC) Antibody
Mouse, Dog, Rat, Human
ICC, IP, WB
APC Conjugated
100 µl/$423; 200 µl/$515; 500 µl/$906; 1 ml/$1,071; 2 ml/$1,420; 5 ml/$2,661
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GHRL / Ghrelin Preproprotein Mouse anti-Human Monoclonal (APC, Cy7) Antibody
Mouse, Dog, Rat, Human
ICC, IP, WB
APC, Cy7 Conjugated
100 µl/$530; 200 µl/$703; 500 µl/$1,217; 1 ml/$1,521; 2 ml/$2,129; 5 ml/$3,991
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GHRL / Ghrelin Preproprotein Mouse anti-Human Monoclonal (Cy3) Antibody
Mouse, Dog, Rat, Human
ICC, IP, WB
Cy3 Conjugated
100 µl/$423; 200 µl/$515; 500 µl/$906; 1 ml/$1,071; 2 ml/$1,420; 5 ml/$2,661
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GHRL / Ghrelin Preproprotein Mouse anti-Human Monoclonal (PE) Antibody
Mouse, Dog, Rat, Human
ICC, IP, WB
PE Conjugated
100 µl/$423; 200 µl/$515; 500 µl/$906; 1 ml/$1,071; 2 ml/$1,420; 5 ml/$2,661
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GHRL / Ghrelin Preproprotein Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
GHRL / Ghrelin Preproprotein Antibody - Immunohistochemistry of paraffin-embedded human stomach using GHRL antibody at dilution of 1:100 (40x lens).
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GHRL / Ghrelin Preproprotein Rabbit anti-Human Polyclonal Antibody
Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
GHRL / Ghrelin Preproprotein Antibody - Immunohistochemistry of paraffin-embedded human placenta using antibody at 1:100 dilution.
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GHRL / Ghrelin Preproprotein Rabbit anti-Human Polyclonal (aa1-117) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
GHRL / Ghrelin Preproprotein Antibody - 1:100 staining human Melanoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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GHRL / Ghrelin Preproprotein Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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GHRL / Ghrelin Preproprotein Rabbit anti-Human Polyclonal Antibody
Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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GHRL / Ghrelin Preproprotein Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452
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GHRL / Ghrelin Preproprotein Rabbit anti-Human Polyclonal (Preservative Free) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated, Preservative Free
50 µg/$343
GHRL / Ghrelin Preproprotein Antibody
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GHRL / Ghrelin Preproprotein Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
Viewing 1-17 of 17 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).