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GHRHR

growth hormone releasing hormone receptor

GHRHR, a Growth Hormone-Releasing Hormone Receptor, is involved in the proliferation and differentiation of somatotrophic pituitary cells and in disease. The GHRH receptor stimulates growth hormone (GH) secretion and synthesis in the pituitary. Mutations in this receptor cause either growth-hormone deficiency, resulting in dwarfism, or excessive production of the hormone, leading to gigantism. Four alternative splice variants have been identified that are tissue specific.

Gene Name: growth hormone releasing hormone receptor
Family/Subfamily: GPCR , Growth hormone releasing hormone
Synonyms: GHRHR, GHRFR, GRFR, IGHD1B, GRF receptor, GH-releasing hormone receptor, GHRH receptor, Ghrh-r
Target Sequences: NM_000823 NP_000814.2 Q02643

Publications (1)

1
GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11. Dayana Abboud, Adrian F Daly, Nadine Dupuis, Mohamed Ali Bahri, Asuka Inoue, Andy Chevigné, Fabien Ectors, Alain Plenevaux, Bernard Pirotte, Albert Beckers, Julien Hanson. Nature communications. 2020 September;11:4752. [Full Text Article] [PubMed:32958754] [PMC:PMC7506554] Related Antibodies: LS-B6566.

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Proteins (3)
Over-Expression Lysate (1)
Recombinant (2)
GHRHR (3)
No (3)
GST, N-terminus (1)
His-GST (1)
Myc-DDK (Flag) (1)
Human (3)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
GHRHR Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
37.3 kDa
100 µg/$494
GHRHR Protein - Recombinant Growth Hormone Releasing Hormone Receptor By SDS-PAGE
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E. coli
His-GST
41.9 kDa
10 µg/$275; 50 µg/$402; 100 µg/$645; 200 µg/$805; 1 mg/$1,881; 500 µg/$1,435; 5 mg/$2,844; 2 mg/$2,065
GHRHR Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).