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GGPS1

geranylgeranyl diphosphate synthase 1

GGPS1 is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, both protein-coding and non-protein-coding, have been found for this gene.

Gene Name: geranylgeranyl diphosphate synthase 1
Synonyms: GGPS1, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Farnesyltranstransferase, GGPPS1, Geranyltranstransferase, GGPP synthase, GGPPS, GGPPSase
Target Sequences: NM_004837 NP_004828.1 O95749

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).