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GFRA3

GDNF family receptor alpha 3

Members of the glial cell line-derived neurotrophic factor (GDNF) family including GDNF and neurturin (NTN) play essential roles in the control of vertebrate neuron survival and differentiation. A new member of the GDNF family was recently identified and designated persephin. Physiological responses to these neurotrophic factors require two receptor subunits, the novel glycosylphosphadidylinositol linked protein GFRa and Ret receptor tyrosine kinase GFRb. Following the findings of GFRa-1 and -2, a novel receptor in GFRa family was identified very recently from human and mouse and designated GFRa-3. GFRa-3 binds persephin, thus, persephin, GFRa-3, and Ret PTK form a complex to transduce persephin signal and to mediate persephin function.

Gene Name: GDNF family receptor alpha 3
Family/Subfamily: GDNF Receptor , Not assigned-Other
Synonyms: GFRA3, GDNF receptor alpha-3, GDNFR-alpha-3, GFR-alpha-3, GDNF family receptor alpha 3, GPI-linked receptor, GDNF family receptor alpha-3, GFRa-3
Target Sequences: NM_001496 NP_001487.2 O60609

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ELISA Kits (3)
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GFRA3 (3)
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Cell Culture Supernatants (3)
Citrate Plasma (2)
EDTA Plasma (2)
Heparin Plasma (2)
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Serum (3)
GFRA3 ELISA Kit
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Sandwich
96-Well Microplate
Human
16.38 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$672
GFRA3 ELISA Kit
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Sandwich
Mouse
15.6 - 1000 pg/ml
Cell Culture Supernatants, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
1 Plate/$795
GFRA3 ELISA Kit
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Sandwich
Human
46.9 - 3000 pg/ml
Cell Culture Supernatants, Citrate Plasma, EDTA Plasma, Heparin Plasma, Serum
1 Plate/$795
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).