GFRA1 / GFR Alpha

GDNF family receptor alpha 1

Glial cell line-derived neurotrophic factor (GDNF) is a potent survival factor for central and peripheral neurons and is essential for the development of kidneys and the enteric nerves system. Physiological responses to GDNF require the presence of a novel glycosylphosphadidylinositol linked protein GDNFRa, which is a cell surface receptor for GDNF. The cDNAs encoding GDNFRa from human, rat, chicken and mouse have been cloned recently. GDNFRa was also termed Ret ligand 1 (RETL1) or TGF-b-related neurotrophic factor receptor 1 (TrnR1) and nominated as GFRa-1 recently. GFRa-1 binds GDNF specifically and mediates activation of the Ret protein tyrosine kinase (PTK). Thus, GDNF, GFRa and the Ret PTK form a complex to transduce GDNF signal and to mediate GDNF function.

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Products

Proteins (20)

Type

Over-Expression Lysate (6)

Recombinant (14)

Target

GFRA1 / GFR Alpha (20)

Publications

No (20)

Tag

6His, C-terminus (2)

Fc (1)

Fc, C-terminus (2)

GST (1)

GST, N-terminus (1)

His (4)

His,C-terminus (1)

His-GST (1)

Myc-DDK (Flag) (7)

Species

Human (13)

Mouse (2)

Rat (2)

Source

293T Cells (3)

E. coli (2)

HEK 293 Cells (4)

Human Cells (6)

Mammalian Cells (3)

Wheat Germ Extract (2)

Purification

Purified (8)

Low Endotoxin Level

Low endotoxin level (9)

Biologically Active

Biologically active (1)

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Human GFRA1 / GFR Alpha Protein (Recombinant 6His, C-terminus) (Asp25-Lys429) - LS-G38980

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

46.28kD

Price:

10 µg/$240; 50 µg/$299; 500 µg/$929; 1 mg/$1,245

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Human GFRA1 / GFR Alpha Protein (Recombinant Fc, C-terminus) (Asp25-Lys429) - LS-G39489

Source:

Human Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

72.3kD

Price:

10 µg/$248; 50 µg/$288; 500 µg/$785; 1 mg/$1,203

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Human GFRA1 / GFR Alpha Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65712

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

48.3 kDa

Price:

20 µg/$1,107

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Human GFRA1 / GFR Alpha Protein (Recombinant GST, N-terminus) (aa267-360) - LS-G58683

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human GFRA1 / GFR Alpha Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76119

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

50.84 kDa

Price:

20 µg/$150

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Human GFRA1 / GFR Alpha Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76120

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.46 kDa

Price:

20 µg/$215

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Human GFRA1 / GFR Alpha Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76121

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

48.3 kDa

Price:

20 µg/$150

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Human GFRA1 / GFR Alpha Protein (Recombinant His) (Met1-Ser424) - LS-G97507

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

46 kDa

Price:

100 µg/$793; 1 mg/$4,191

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Human GFRA1 / GFR Alpha Protein (Recombinant His) (aa239-350) - LS-G16142

Source:

E. coli

Tag:

His

Molecular Weight:

14.0 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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Mouse GFRA1 / GFR Alpha Protein (Recombinant His-GST) (aa239-350) - LS-G26115

Source:

E. coli

Tag:

His-GST

Molecular Weight:

42.4 kDa

Price:

10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090

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Human GFRA1 / GFR Alpha Protein (Recombinant GST) (Full Length) - LS-G28614

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

77.2 kDa

Price:

2 µg/$439

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Human GFRA1 / GFR Alpha Protein (Recombinant 6His, C-terminus) (Full Length) - LS-G136818

Source:

Mammalian Cells

Tag:

6His, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

46.28 kDa

Price:

50 µg/$327; 10 µg/$250; 1 mg/$1,518; 500 µg/$1,170

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GFRA1 / GFR Alpha Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G126725

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

50.84 kDa

Price:

100 µg/$494

Select

GFRA1 / GFR Alpha Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116080

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.46 kDa

Price:

100 µg/$710

Select

Human GFRA1 / GFR Alpha Protein (Recombinant His,C-terminus) (Asp25-Lys429) - LS-G138671

Source:

Mammalian Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

46.28 kDa

Price:

10 µg/$240; 50 µg/$299

Select

Human GFRA1 / GFR Alpha Protein (Recombinant Fc, C-terminus) (Asp25-Lys429) - LS-G138619

Source:

Mammalian Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

72.3 kDa

Price:

10 µg/$248; 50 µg/$288

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Rat GFRA1 / GFR Alpha Protein (Recombinant His) (Met1-Leu445) - LS-G98399

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

48 kDa

Price:

100 µg/$926

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Rat GFRA1 / GFR Alpha Protein (Recombinant Fc) (Met1-Leu445) - LS-G98400

Source:

Human Cells

Tag:

Fc

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

73.8 kDa

Price:

100 µg/$926

Select

Mouse GFRA1 / GFR Alpha Protein (Recombinant His) (Met1-Ser425) - LS-G98787

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

46.3 kDa

Price:

100 µg/$843

Select

GFRA1 / GFR Alpha Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G106600

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

48.3 kDa

Price:

100 µg/$494

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