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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
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GFRA1 / GFR Alpha

GDNF family receptor alpha 1

Glial cell line-derived neurotrophic factor (GDNF) is a potent survival factor for central and peripheral neurons and is essential for the development of kidneys and the enteric nerves system. Physiological responses to GDNF require the presence of a novel glycosylphosphadidylinositol linked protein GDNFRa, which is a cell surface receptor for GDNF. The cDNAs encoding GDNFRa from human, rat, chicken and mouse have been cloned recently. GDNFRa was also termed Ret ligand 1 (RETL1) or TGF-b-related neurotrophic factor receptor 1 (TrnR1) and nominated as GFRa-1 recently. GFRa-1 binds GDNF specifically and mediates activation of the Ret protein tyrosine kinase (PTK). Thus, GDNF, GFRa and the Ret PTK form a complex to transduce GDNF signal and to mediate GDNF function.

Gene Name: GDNF family receptor alpha 1
Family/Subfamily: GDNF Receptor , Not assigned-Other
Synonyms: GFRA1, GDNF receptor alpha-1, GDNFRA, GFR-ALPHA-1, GDNF family receptor alpha-1, GDNFR, GDNFR-alpha-1, RET ligand 1, RETL1, TRNR1, RET1L, GDNF family receptor alpha 1, GPI-linked anchor protein
Target Sequences: NM_005264 NP_005255.1 P56159


GFRA1 / GFR Alpha Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Rabbit Polyclonal to Human GFRA1 / GFR Alpha
Pig, Human
IHC, IHC-P, WB
Unconjugated
100µl   0.5mg/ml   $485.00
GFRA1 / GFR Alpha Antibody - Immunohistochemistry of GFRa-1 in human brain tissue with GFRa-1 antibody at 1 µg/ml.
Select
Rabbit Polyclonal (IgG) to Human GFRA1 / GFR Alpha
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.1mg   1mg/ml   $375.00
GFRA1 / GFR Alpha Antibody - Immunofluorescence analysis of U20S cell using GFRA1 antibody. Blue: DAPI for nuclear staining.
Select
Rabbit Polyclonal (IgG) to Human GFRA1 / GFR Alpha
Mouse, Human
IF, IHC, WB
Unconjugated
20µl   $215.00; 50µl   $235.00; 100µl   $315.00; 200µl   $425.00
GFRA1 / GFR Alpha Antibody - Immunofluorescence of monoclonal antibody to GFRA1 on HeLa cell . [antibody concentration 10 ug/ml]
Select
Mouse Monoclonal [clone 1G4] (IgG2a,k) to Human GFRA1 / GFR Alpha
Human
ELISA, IF, WB
Unconjugated
100µg   $365.00
GFRA1 / GFR Alpha Antibody - Immunohistochemistry of paraffin-embedded human breast cancer using GFRA1 Antibody at dilution of 1:100
Select
Rabbit Polyclonal (IgG) to Human GFRA1 / GFR Alpha
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50µg   $285.00; 100µg   $385.00
GFRA1 / GFR Alpha Antibody - Immunohistochemistry - Anti-GFRA1/Gfr Alpha 1 Picoband Antibody
Select
Rabbit Polyclonal to Human GFRA1 / GFR Alpha
Human
IHC, IHC-P, WB
Unconjugated
100µg   $355.00
GFRA1 / GFR Alpha Antibody - 1:100 staining human liver carcinoma tissues by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
Rabbit Polyclonal (IgG) to Human GFRA1 / GFR Alpha
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
Select
Rabbit Polyclonal to Mouse GFRA1 / GFR Alpha
Mouse
ELISA, IHC, IHC-P
Unconjugated
50µl   $245.00; 100µl   $305.00
GFRA1 / GFR Alpha Antibody - IHC-P: GFRA1 antibody testing of human lung cancer tissue
Select
Rabbit Polyclonal (IgG) to Human GFRA1 / GFR Alpha
Human
IHC, IHC-P, WB
Unconjugated
100µg   $435.00
Select
Rabbit Polyclonal (IgG) to Human GFRA1 / GFR Alpha
Mouse, Rat, Human
ELISA, IHC
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
GFRA1 / GFR Alpha Antibody - Immunohistochemistry analysis of paraffin-embedded human brain tissue, using GFR alpha-1 Antibody. The picture on the right is blocked with the synthesized peptide.
Select
Rabbit Polyclonal (IgG) to Human GFRA1 / GFR Alpha
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
Select
Rabbit Polyclonal to Mouse GFRA1 / GFR Alpha
Mouse
ELISA, WB
Unconjugated
50µl   $235.00; 100µl   $275.00; 200µl   $305.00
GFRA1 / GFR Alpha Antibody - IHC of GFR -1 (K90) pAb in paraffin-embedded human brain tissue.
Select
Rabbit Polyclonal to Human GFRA1 / GFR Alpha
Mouse, Rat, Human
IHC, IHC-P
Unconjugated
100µl   $345.00
GFRA1 / GFR Alpha Antibody - Western blot analysis of 293T cell, using GFRA1 Polyclonal Antibody at dilution of 1:1250.
Select
Rabbit Polyclonal (IgG) to Human GFRA1 / GFR Alpha
Mouse, Rat, Human
ELISA, WB
Unconjugated
20µl   0.7mg/ml   $205.00; 60µl   0.7mg/ml   $235.00; 120µl   0.7mg/ml   $295.00; 200µl   0.7mg/ml   $395.00
Select
Rabbit Polyclonal (IgG) to Human GFRA1 / GFR Alpha
Mouse, Rat, Human
IHC, WB
HRP Conjugated
100µl   $770.00
Select
Rabbit Polyclonal (IgG) to Human GFRA1 / GFR Alpha
Mouse, Rat, Human
IHC, WB
Biotin Conjugated
100µl   $770.00
Select
Rabbit Polyclonal (IgG) to Human GFRA1 / GFR Alpha
Mouse, Rat, Human
IHC, WB
FITC Conjugated
100µl   $770.00
Select
Rabbit Polyclonal (IgG) to Human GFRA1 / GFR Alpha
Mouse, Rat, Human
IHC, WB
AP Conjugated
100µl   $770.00
Select
Rabbit Polyclonal (IgG) to Human GFRA1 / GFR Alpha
Mouse, Rat, Human
IHC, WB
PE Conjugated
100µl   $770.00
Select
Rabbit Polyclonal to Mouse GFRA1 / GFR Alpha
Mouse
ELISA
Unconjugated
100µl   $235.00; 200µl   $275.00; 400µl   $305.00
GFRA1 / GFR Alpha Antibody - Western blot of GFRA1 / GFR Alpha antibody.
Select
Rabbit Polyclonal to Mouse GFRA1 / GFR Alpha
Mouse
WB
Unconjugated
100µl   0.5mg/ml   $275.00; 200µl   0.5mg/ml   $315.00; 500µl   0.5mg/ml   $475.00; 1ml   0.5mg/ml   $590.00
GFRA1 / GFR Alpha Antibody - Western blot of GFRA1 / GFR Alpha antibody.
Select
Rabbit Polyclonal to Mouse GFRA1 / GFR Alpha
Mouse
WB
FITC Conjugated
200µl   0.5mg/ml   $385.00; 500µl   0.5mg/ml   $665.00; 1ml   0.5mg/ml   $830.00
GFRA1 / GFR Alpha Antibody - Western blot of GFRA1 / GFR Alpha antibody.
Select
Rabbit Polyclonal to Mouse GFRA1 / GFR Alpha
Mouse
WB
Cy3 Conjugated
200µl   0.1mg/ml   $475.00; 500µl   0.1mg/ml   $950.00; 1ml   0.1mg/ml   $1,185.00
GFRA1 / GFR Alpha Antibody - Western blot of GFRA1 / GFR Alpha antibody.
Select
Rabbit Polyclonal to Mouse GFRA1 / GFR Alpha
Mouse
WB
APC Conjugated
200µl   0.1mg/ml   $475.00; 500µl   0.1mg/ml   $950.00; 1ml   0.1mg/ml   $1,185.00
Select
Rabbit Polyclonal to Human GFRA1 / GFR Alpha
Mouse, Rat, Human
WB
Unconjugated
100µg   0.5mg/ml   $425.00
Viewing 1-25 of 43 products



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).