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GFER

growth factor, augmenter of liver regeneration

Isoform 1: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen.Isoform 2: May act as an autocrine hepatotrophic growth factor promoting liver regeneration.

Gene Name: growth factor, augmenter of liver regeneration
Synonyms: GFER, ERV1, HPO1, HPO2, HPO, HSS, Hepatopoietin, ALR, ERV1 homolog, Erv1-like growth factor, Hepatopoietin protein, HERV1
Target Sequences: NM_005262 NP_005253.3 P55789

☰ Filters
Products
Proteins (9)
Over-Expression Lysate (2)
Recombinant (7)
GFER (9)
No (9)
6His, N-terminus (2)
6His-SUMO, N-terminus (1)
GST (1)
His (1)
His-S (1)
Myc-DDK (Flag) (3)
Human (6)
Mouse (1)
Rat (1)
293T Cells (1)
E. coli (5)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (4)
Low endotoxin level (2)
GFER Protein - Purified recombinant protein GFER was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
23.3 kDa
20 µg/$1,107
GFER Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
6His-SUMO, N-terminus
1 mg/$1,679; 100 µg/$500; 20 µg/$364
GFER Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
23.3 kDa
20 µg/$150
GFER Protein - Recombinant  Growth Factor, Augmenter Of Liver Regeneration By SDS-PAGE
Select
E. coli
His-S
25.4 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
GFER Protein - 12.5% SDS-PAGE of human GFER stained with Coomassie Blue
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Wheat Germ Extract
GST
39.49 kDa
10 µg/$479; 25 µg/$670
Select
E. coli
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
17.3kD
10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157
Select
E. coli
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
17.3 kDa
10 µg/$281; 50 µg/$389
GFER Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
23.3 kDa
100 µg/$494
GFER Protein
Select
E. coli
His
50 µg/$361; 250 µg/$739; 10 µg/$261
Viewing 1-9 of 9 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).