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GDF5 / GDF-5

growth differentiation factor 5

GDF5 / GDF-5 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type; brachydactyly, type C; and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development.

Gene Name: growth differentiation factor 5
Family/Subfamily: TGF beta
Synonyms: GDF5, CDMP-1, CDMP1, GDF-5, LAP4, Radotermin, OS5, BMP14, SYNS2
Target Sequences: NM_000557 NP_000548.2 P43026

☰ Filters
Products
Proteins (13)
Over-Expression Lysate (2)
Recombinant (11)
GDF5 / GDF-5 (13)
No (13)
GST, N-terminus (1)
His (3)
His, N-Terminal (1)
His-S (1)
His-T7 (1)
Myc-DDK (Flag) (2)
Human (9)
Mouse (3)
293T Cells (1)
E. coli (10)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (4)
Low endotoxin level (5)
Biologically active (2)
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
27.0 kDa
10 µg/$268; 50 µg/$349
GDF5 / GDF-5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
55.41 kDa
100 µg/$494
GDF5 / GDF-5 Protein - Recombinant Growth Differentiation Factor 5 By SDS-PAGE
Select
E. coli
His, N-Terminal
15.1 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
GDF5 / GDF-5 Protein
Select
E. coli
His
17.7 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
GDF5 / GDF-5 Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
GDF5 / GDF-5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
55.41 kDa
20 µg/$150
GDF5 / GDF-5 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
27.0 kDa
10 µg/$268; 50 µg/$349
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
13.7kD
50 µg/$343; 500 µg/$905; 1 mg/$1,329; 10 µg/$255
GDF5 / GDF-5 Protein
Select
E. coli
His
Less than 1.0 EU/µg protein (determined by LAL method).
100 µg/$361; 500 µg/$739; 20 µg/$261
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
13.7 kDa
20 µg/$360; 100 µg/$728
Select
E. coli
His-S
21.6 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
GDF5 / GDF-5 Protein - Recombinant Growth Differentiation Factor 5 By SDS-PAGE
Select
E. coli
His-T7
50.2 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
Viewing 1-13 of 13 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).