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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
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GDF2 / BMP9
growth differentiation factor 2
GDF2 / BMP9 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein plays a role in the adult liver and in differentiation of cholinergic central nervous system neurons. Mutations in this gene are associated with hereditary hemorrhagic telangiectasia.
| Gene Name: | growth differentiation factor 2 |
| Family/Subfamily: | TGF beta , not assigned-TGF beta |
| Synonyms: | GDF2, BMP-9, BMP9, GDF-2, Bone morphogenetic protein 9 |
| Target Sequences: | NM_016204 NP_057288.1 Q9UK05 |
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