Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
GCS1 / MOGS is the first enzyme in the N-linked oligosaccharide processing pathway. The enzyme cleaves the distal alpha-1,2-linked glucose residue from the Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor. This protein is located in the lumen of the endoplasmic reticulum. Defects in this gene are a cause of type IIb congenital disorder of glycosylation (CDGIIb). Two transcript variants encoding different isoforms have been found for this gene.
Gene Name: | mannosyl-oligosaccharide glucosidase |
Synonyms: | MOGS, CDG2B, CWH41, DER7, Glucosidase I, Processing A-glucosidase I, GCS1 |
Target Sequences: | NM_006302 NP_006293.2 Q13724 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.