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GCKR

glucokinase (hexokinase 4) regulator

Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.

Gene Name: glucokinase (hexokinase 4) regulator
Synonyms: GCKR, GKRP, FGQTL5, Glucokinase regulator, Glucokinase regulatory protein
Target Sequences: NM_001486 NP_001477.2 Q14397

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Products
Proteins (9)
Over-Expression Lysate (2)
Recombinant (7)
GCKR (9)
No (9)
6His, N-terminus (1)
His (3)
His-SUMO (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (5)
Mouse (1)
Rat (2)
293T Cells (1)
E. coli (5)
HEK 293 Cells (2)
Yeast (1)
GCKR Protein
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Yeast
6His, N-terminus
70.69 kD
1 mg/$1,607; 100 µg/$469; 20 µg/$349
GCKR Protein
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E. coli
His-SUMO
84.6 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
GCKR Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
69.1 kDa
20 µg/$215
GCKR Protein - Purified recombinant protein GCKR was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
68.5 kDa
20 µg/$1,107
GCKR Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
69.1 kDa
100 µg/$710
GCKR Protein - Recombinant Glucokinase Regulatory Protein By SDS-PAGE
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E. coli
His-T7
30.5 kDa
50 µg/$472; 10 µg/$286; 200 µg/$942; 100 µg/$752; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
GCKR Protein - Recombinant Glucokinase Regulatory Protein By SDS-PAGE
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E. coli
His
22.3 kDa
10 µg/$297; 50 µg/$542; 100 µg/$865; 200 µg/$1,065; 1 mg/$2,239; 500 µg/$1,755; 5 mg/$3,781; 2 mg/$2,430
GCKR Protein - Recombinant Glucokinase Regulatory Protein By SDS-PAGE
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E. coli
His
22.6 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
GCKR Protein - Recombinant Glucokinase Regulatory Protein By SDS-PAGE
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E. coli
His
21.7 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).