GCD / GCDH

glutaryl-CoA dehydrogenase

GCD / GCDH belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Mutations in this gene result in the metabolic disorder glutaric aciduria type 1, which is also known as glutaric acidemia type I. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 12.

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Products

Proteins (14)

Type

Over-Expression Lysate (6)

Recombinant (8)

Target

GCD / GCDH (14)

Application

SDS-PAGE (1)

Publications

No (14)

Tag

6His, N-terminus (2)

GST, N-terminus (1)

His (1)

His,C-terminus (1)

His-T7, N-terminus (2)

Myc-DDK (Flag) (7)

Species

Human (10)

Mouse (1)

Source

293T Cells (3)

Baculovirus (1)

E. coli (5)

HEK 293 Cells (4)

Wheat Germ Extract (1)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (3)

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Human GCD / GCDH Protein (Recombinant GST, N-terminus) (Full Length) - LS-G28592

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Molecular Weight:

74.5 kDa

Price:

10 µg/$479; 25 µg/$670

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GCD / GCDH Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G123360

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

48.13 kDa

Price:

100 µg/$494

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GCD / GCDH Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G127053

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47.36 kDa

Price:

100 µg/$494

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GCD / GCDH Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G114228

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47.36 kDa

Price:

100 µg/$710

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Human GCD / GCDH Protein (Recombinant His,C-terminus) (Met1-Lys438) - LS-G141203

Source:

Baculovirus

Tag:

His,C-terminus

Application:

SDS-PAGE

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant human GCDH consists of 405 amino acids and predicts a molecular mass of 44.9 kDa.

Price:

100 µg/$480

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Human GCD / GCDH Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76192

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

48.13 kDa

Price:

20 µg/$150

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Human GCD / GCDH Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76193

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47.36 kDa

Price:

20 µg/$150

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Human GCD / GCDH Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76198

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47.36 kDa

Price:

20 µg/$215

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Human GCD / GCDH Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65747

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.4 kDa

Price:

20 µg/$1,107

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Human GCD / GCDH Protein (Recombinant His) - LS-G845

Source:

E. coli

Tag:

His

Price:

50 µg/$411; 250 µg/$985; 10 µg/$276; 20 µg/$323; 100 µg/$544; 500 µg/$1,388

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Human GCD / GCDH Protein (Recombinant 6His, N-terminus) (Arg45-Lys438) - LS-G139594

Source:

E. coli

Tag:

6His, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

45.0 kDa

Price:

10 µg/$376; 50 µg/$526

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Human GCD / GCDH Protein (Recombinant 6His, N-terminus) (Arg45-Lys438) - LS-G39725

Source:

E. coli

Tag:

6His, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

45kD

Price:

10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157

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Human GCD / GCDH Protein (Recombinant His-T7, N-terminus) (Glu270-Lys438) - LS-G133347

Source:

E. coli

Tag:

His-T7, N-terminus

Molecular Weight:

22.1kDa

Price:

10 µg/$263; 50 µg/$340; 200 µg/$650; 100 µg/$520; 1 mg/$1,636; 500 µg/$1,225; 5 mg/$2,577; 2 mg/$1,810

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Mouse GCD / GCDH Protein (Recombinant His-T7, N-terminus) (Glu270-Lys438) - LS-G133483

Source:

E. coli

Tag:

His-T7, N-terminus

Molecular Weight:

22.1kDa

Price:

10 µg/$267; 50 µg/$355; 200 µg/$710; 100 µg/$567; 1 mg/$1,735; 500 µg/$1,308; 5 mg/$2,687; 2 mg/$1,914

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