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Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector it is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. May also play a role in transport between the recycling endosomes and the Golgi. Required for maintenance of the Golgi structure, it is involved in the biogenesis of noncentrosomal, Golgi-associated microtubules through recruitment of CLASP1 and CLASP2.
Gene Name: | GRIP and coiled-coil domain containing 2 |
Synonyms: | GCC2, CLL-associated antigen KW-11, CTCL tumor antigen se1-1, GCC185, GCC protein, 185-kD, Ran-binding protein 2-like 4, RANBP2L4, REN53, KIAA0336 |
Target Sequences: | NM_014635 NP_055450.1 Q8IWJ2 |
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