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Unfortunately, the antibody (ID:63416) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



GC1qR / C1QBP

complement component 1, q subcomponent binding protein

Is believed to be a multifunctional and multicompartmental protein involved in inflammation and infection processes, ribosome biogenesis, regulation of apoptosis, transcriptional regulation and pre-mRNA splicing. At the cell surface is thought to act as an endothelial receptor for plasma proteins of the complement and kallikrein-kinin cascades. Putative receptor for C1q; specifically binds to the globular "heads" of C1q thus inhibiting C1; may perform the receptor function through a complex with C1qR/CD93. In complex with cytokeratin-1/KRT1 is a high affinity receptor for kininogen-1/HMWK. Can also bind other plasma proteins, such as coagulation factor XII leading to its autoactivation. May function to bind initially fluid kininogen-1 to the cell membrane. The secreted form may enhance both extrinsic and intrinsic coagulation pathways. It is postulated that the cell surface form requires docking with transmembrane proteins for downstream signaling which might be specific for a cell-type or response. By acting as C1q receptor is involved in chemotaxis of immature dendritic cells and neutrophils and is proposed to signal through CD209/DC-SIGN on immature dendritic cells, through integrin alpha-4/beta-1 during trophoblast invasion of the decidua, and through integrin beta-1 during endothelial cell adhesion and spreading. Signaling involved in inhibition of innate immune response is implicating the PI3K-AKT/PKB pathway. In mitochondrial translation may be involved in formation of functional 55S mitoribosomes; the function seems to involve its RNA-binding activity. May be involved in the nucleolar ribosome maturation process; the function may involve the exchange of FBL for RRP1 in the association with pre-ribosome particles. Involved in regulation of RNA splicing by inhibiting the RNA-binding capacity of SRSF1 and its phosphorylation. Is required for the nuclear translocation of splicing factor U2AF1L4. Involved in regulation of CDKN2A- and HRK-mediated apoptosis. Stabilizes mitochondrial CDKN2A isoform smARF. May be involved in regulation of FOXC1 transcriptional activity and NFY/CCAAT-binding factor complex-mediated transcription. In infection processes acts as an attachment site for microbial proteins, including Listeria monocytogenes internalin B and Staphylococcus aureus protein A. May play a role in antibacterial defense as it can bind to cell surface hyaluronan and inhibit Streptococcus pneumoniae hyaluronate lyase. Involved in replication of Rubella virus. May be involved in modulation of the immune response; ligation by HCV core protein is resulting in suppresion of interleukin-12 production in monocyte-derived dendritic cells. Involved in regulation of antiviral response by inhibiting DDX58- and IFIH1-mediated signaling pathways probably involving its association with MAVS after viral infection. Involved in HIV-1 replication, presumably by contributing to splicing of viral RNA.

Gene Name: complement component 1, q subcomponent binding protein
Synonyms: C1QBP, GC1Q-R, GC1q-R protein, GC1QBP, HABP1, GC1qR, p33, p32, Glycoprotein gC1qBP, Hyaluronan-binding protein 1, SF2p32
Target Sequences: NM_001212 NP_001203.1 Q07021

Filtered By: None
Target
gc1qr-c1qbp (63)
Reactivity
Human (50)
Mouse (29)
Rat (28)
Bat (1)
Bovine (2)
Cow (1)
Dog (1)
Hamster (3)
Horse (2)
Application
IHC (3)
IHC-P (9)
WB (56)
Flo (22)
ELISA (29)
Func (5)
ICC (4)
IF (9)
IP (24)
RIA (1)
Host
rabbit (36)
mouse (27)
Isotype
IgG (22)
IgG1 (5)
IgG1,k (19)
Clonality
monoclonal mc (26)
polyclonal pc (37)
Clone
1F3 (1)
60.11 (5)
74.5.2 (1)
GF1 (1)
Format
AP Conjugated (2)
APC Conjugated (2)
Biotin Conjugated (7)
FITC Conjugated (9)
HRP Conjugated (2)
Low Endotoxin (1)
PE Conjugated (2)
Unconjugated (39)
Epitope
aa71-278 (6)
aa74-282 (4)
aa72-279 (3)
aa76-282 (3)
Internal (1)
Lys100 (1)
aa1-282 (1)
aa150-200 (1)
aa221-249 (1)
aa232-282 (1)
aa30-110 (1)
aa50-100 (1)
aa51-85 (1)
aa61-110 (1)
aa76-104 (1)
Publications
No (63)
Showing 1-25 out of 63 results
Anti-GC1qR / C1QBP Antibody (aa74-282) IHC-plus™ LS-B7311

Mouse Monoclonal (IgG1) to Human GC1qR / C1QBP
Human
ELISA Flo Func IF IHC-P WB
Unconjugated
Anti-GC1qR / C1QBP Antibody (clone 60.11, FITC) LS-C62841

Mouse Monoclonal [clone 60.11] (IgG1,k) to Human GC1qR / C1QBP
Human
ELISA Flo WB
FITC Conjugated
Anti-GC1qR / C1QBP Antibody (clone 60.11) LS-C34554

Mouse Monoclonal [clone 60.11] (IgG1,k) to Human GC1qR / C1QBP
Human
ELISA Flo WB
Unconjugated
Anti-GC1qR / C1QBP Antibody LS-C14517

Mouse Monoclonal (IgG1,k) to Human GC1qR / C1QBP
Mouse, Rat, Human
ELISA Flo IP WB
Unconjugated
Anti-GC1qR / C1QBP Antibody (HRP) LS-C545235

Mouse Monoclonal (IgG1,k) to Human GC1qR / C1QBP
Mouse, Rat, Human
ELISA Flo IP WB
HRP Conjugated
Anti-GC1qR / C1QBP Antibody (Biotin) LS-C525109

Mouse Monoclonal (IgG1,k) to Human GC1qR / C1QBP
Mouse, Rat, Human
ELISA Flo IP WB
Biotin Conjugated
Anti-GC1qR / C1QBP Antibody (FITC) LS-C535125

Mouse Monoclonal (IgG1,k) to Human GC1qR / C1QBP
Mouse, Rat, Human
ELISA Flo IP WB
FITC Conjugated
Anti-GC1qR / C1QBP Antibody (PE) LS-C653316

Mouse Monoclonal (IgG1,k) to Human GC1qR / C1QBP
Mouse, Rat, Human
ELISA Flo IP WB
PE Conjugated
Anti-GC1qR / C1QBP Antibody (APC) LS-C516089

Mouse Monoclonal (IgG1,k) to Human GC1qR / C1QBP
Mouse, Rat, Human
ELISA Flo IP WB
APC Conjugated
Anti-GC1qR / C1QBP Antibody IHC-plus™ LS-B3069

Rabbit Polyclonal (IgG) to Human GC1qR / C1QBP
Dog, Horse, Bat, Human
ELISA IHC-P
Unconjugated
Anti-GC1qR / C1QBP Antibody (aa74-282, clone 60.11) IHC-plus™ LS-B14761

Mouse Monoclonal [clone 60.11] (IgG1) to Human GC1qR / C1QBP
Rat, Hamster, Human
Flo Func IHC-P IP WB
Unconjugated
Anti-GC1qR / C1QBP Antibody LS-C483828

Mouse Monoclonal to Human GC1qR / C1QBP
Human
ELISA ICC IF IP WB
Unconjugated
Anti-GC1qR / C1QBP Antibody LS-C14518

Mouse Monoclonal (IgG1,k) to Human GC1qR / C1QBP
Mouse, Rat, Human
ELISA Flo IP WB
Unconjugated
Anti-GC1qR / C1QBP Antibody (HRP) LS-C545234

Mouse Monoclonal (IgG1,k) to Human GC1qR / C1QBP
Mouse, Rat, Human
ELISA Flo IP WB
HRP Conjugated
Anti-GC1qR / C1QBP Antibody (Biotin) LS-C525112

Mouse Monoclonal (IgG1,k) to Human GC1qR / C1QBP
Mouse, Rat, Human
ELISA Flo IP WB
Biotin Conjugated
Anti-GC1qR / C1QBP Antibody (FITC) LS-C535128

Mouse Monoclonal (IgG1,k) to Human GC1qR / C1QBP
Mouse, Rat, Human
ELISA Flo IP WB
FITC Conjugated
Anti-GC1qR / C1QBP Antibody (PE) LS-C653319

Mouse Monoclonal (IgG1,k) to Human GC1qR / C1QBP
Mouse, Rat, Human
ELISA Flo IP WB
PE Conjugated
Anti-GC1qR / C1QBP Antibody (APC) LS-C516092

Mouse Monoclonal (IgG1,k) to Human GC1qR / C1QBP
Mouse, Rat, Human
ELISA Flo IP WB
APC Conjugated
Anti-GC1qR / C1QBP Antibody LS-C483821

Mouse Monoclonal to Human GC1qR / C1QBP
Human
Flo ICC IF
Unconjugated
Anti-GC1qR / C1QBP Antibody LS-C331747

Rabbit Polyclonal (IgG) to Human GC1qR / C1QBP
Mouse, Rat, Human
IF IHC WB
Unconjugated
Anti-GC1qR / C1QBP Antibody (Low Endotoxin) LS-C663045

Mouse Monoclonal (IgG1) to Human GC1qR / C1QBP
Rat, Human
Flo Func IP RIA WB
Unconjugated, Low Endotoxin
Anti-GC1qR / C1QBP Antibody (aa74-282, clone GF1, FITC) LS-C189916

Mouse Monoclonal [clone GF1] (IgG1) to Human GC1qR / C1QBP
Rat, Hamster, Human
ELISA Flo Func IP WB
FITC Conjugated
Anti-GC1qR / C1QBP Antibody (aa61-110) IHC-plus™ LS-B7064

Rabbit Polyclonal (IgG) to Human GC1qR / C1QBP
Mouse, Rat, Human
ELISA IHC-P WB
Unconjugated
Anti-GC1qR / C1QBP Antibody (aa150-200) LS-C289576

Rabbit Polyclonal (IgG) to Human GC1qR / C1QBP
Mouse, Horse, Human
IF IHC-P IP WB
Unconjugated
Anti-GC1qR / C1QBP Antibody (clone 74.5.2) LS-C34555

Mouse Monoclonal [clone 74.5.2] (IgG1,k) to Human GC1qR / C1QBP
Human
ELISA Flo WB
Unconjugated

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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