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Multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. In plasma, it carries the vitamin D sterols and prevents polymerization of actin by binding its monomers. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes.
Gene Name: | group-specific component (vitamin D binding protein) |
Synonyms: | GC, Gc-globulin, HDBP, Group-specific component, GRD3, VDB, VDBG, VDBP, Vitamin D-binding protein |
Target Sequences: | NM_000583 NP_000574.2 P02774 |
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