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GBAS

glioblastoma amplified sequence

Chromosomal region 7p12, which contains GBAS, is amplified in approximately 40% of glioblastomas, the most common and malignant form of central nervous system tumor. The predicted 286-amino acid protein contains a signal peptide, a transmembrane domain, and 2 tyrosine phosphorylation sites. The GBAS transcript is expressed most abundantly in heart and skeletal muscle. GBAS protein might be involved in vesicular transport.

Gene Name:	glioblastoma amplified sequence
Synonyms:	GBAS, NIPSNAP2, Protein NipSnap homolog 2
Target Sequences:	NM_001483 NP_001474.1 O75323

Publications (1)

NIPSNAP1 and NIPSNAP2 Act as "Eat Me" Signals for Mitophagy. Yakubu Princely Abudu, Serhiy Pankiv, Benan John Mathai, Alf Håkon Lystad, Christian Bindesbøll, Hanne Britt Brenne, Matthew Yoke Wui Ng, Bernd Thiede, Ai Yamamoto, Thaddaeus Mutugi Nthiga, Trond Lamark, Camila V Esguerra, Terje Johansen, Anne Simonsen. Developmental cell. 2019 May;49:509-525e12. [Full Text Article] [PubMed:30982665] Related Antibodies: LS-B13280.

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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