GALR2 / Galanin Receptor 2

galanin receptor 2

Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways.

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Products

ELISA Kits (4)

Type

Custom (2)

Sandwich (2)

Target

GALR2 / Galanin Receptor 2 (4)

Reactivity

Human (1)

Mouse (1)

Rat (2)

Format

96-Well Strip Plate (4)

Publications

No (4)

Sample Type

Plasma (2)

Serum (2)

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Rat GALR2 / Galanin Receptor 2 (Sandwich ELISA) ELISA Kit - LS-F38764

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

1.25 - 80 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Mouse GALR2 / Galanin Receptor 2 (Custom) ELISA Kit - LS-F66294

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Price:

1 Plate/$783

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Rat GALR2 / Galanin Receptor 2 (Custom) ELISA Kit - LS-F65512

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Price:

1 Plate/$783

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Human GALR2 / Galanin Receptor 2 (Sandwich ELISA) ELISA Kit - LS-F66974

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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