Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
GALNT8 is a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression.
Gene Name: | Udp-n-acetyl-alpha-d-galactosamine:polypeptide N-acetylgalactosaminyltransferase 8 (GALNAC-T8) |
Synonyms: | GALNT8, GalNAc transferase 8, GALNAC-T8, Pp-GaNTase 8 |
Target Sequences: | NM_017417 NP_059113.1 Q9NY28 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.