GALNT4

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)

GALNT4 is a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. In vitro, the encoded protein can complement other GalNAc-Ts in the complete O-glycosylation of the mucin-1 tandem repeat and can O-glycosylate the P-selectin glycoprotein ligand-1 molecule. The coding region of this gene is contained within a single exon. Fusion transcripts, which combine part of this gene with the 5' exons of the neighboring POC1B (POC1 centriolar protein homolog B) gene, also exist.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

GALNT4 (3)

Publications

No (3)

Tag

GST (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human GALNT4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G89203

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

66.5 kDa

Price:

20 µg/$150

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Human GALNT4 Protein (Recombinant GST) (Full Length) - LS-G31279

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

85.03 kDa

Price:

10 µg/$479; 25 µg/$670

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GALNT4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117099

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

66.5 kDa

Price:

100 µg/$494

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