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GALE / UDP-Glucose 4-Epimerase

UDP-galactose-4-epimerase

GALE is UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified.

Gene Name: UDP-galactose-4-epimerase
Synonyms: GALE, Galactowaldenase, Galactose-4-epimerase, UDP-, UDP-glucose 4-epimerase, SDR1E1, UDP galactose-4-epimerase, UDP-galactose 4-epimerase, UDP-galactose-4-epimerase
Target Sequences: NM_000403 NP_000394.2 Q14376

☰ Filters
Antibodies (37)
Proteins (14)
Over-Expression Lysate (6)
Primary (37)
Recombinant (8)
GALE / UDP-Glucose 4-Epimerase (51)
Human (37)
Mouse (3)
Rat (5)
Bat (3)
Bovine (3)
Chimpanzee (6)
Dog (8)
Gibbon (6)
Hamster (3)
Horse (3)
Monkey (5)
Orangutan (6)
Pig (3)
Rabbit (3)
IHC (11)
IHC-P (8)
WB (36)
Flo (2)
ELISA (14)
ICC (2)
IF (5)
IP (1)
Peptide-ELISA (1)
rabbit (33)
mouse (4)
IgG (26)
IgG1 (2)
IgG1,k (1)
monoclonal mc (3)
polyclonal pc (34)
AT6G10 (1)
OTI1C4 (2)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (5)
Carrier-free (1)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (2)
Unconjugated (18)
aa142-171 (7)
N-Terminus (4)
aa1-348 (4)
aa201-250 (4)
No (51)
6His, N-terminus (2)
GST (1)
His (1)
His-SUMO (1)
Myc-DDK (Flag) (9)
Human (11)
293T Cells (3)
E. coli (4)
HEK 293 Cells (6)
Wheat Germ Extract (1)
Purified (1)
Low endotoxin level (2)
GALE / UDP-Glucose 4-Epimerase Antibody - Formalin-fixed and paraffin-embedded human skin tissue reacted with GALE Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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GALE / UDP-Glucose 4-Epimerase Rabbit anti-Human Polyclonal (aa142-171) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
GALE / UDP-Glucose 4-Epimerase Antibody - IHC analysis of GALE using anti-GALE antibody. GALE was detected in paraffin-embedded section of mouse intestine tissue. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1µg/ml rabbit anti-GALE Antibody overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen.
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GALE / UDP-Glucose 4-Epimerase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
GALE / UDP-Glucose 4-Epimerase Antibody - Immunohistochemistry of paraffin-embedded human kidney using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GALE / UDP-Glucose 4-Epimerase Rabbit anti-Human Polyclonal (aa1-348) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
GALE / UDP-Glucose 4-Epimerase Antibody - Immunohistochemistry of paraffin-embedded human kidney using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GALE / UDP-Glucose 4-Epimerase Rabbit anti-Human Polyclonal (aa1-348) (HRP) Antibody
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
GALE / UDP-Glucose 4-Epimerase Antibody - Immunohistochemistry of paraffin-embedded human kidney using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GALE / UDP-Glucose 4-Epimerase Rabbit anti-Human Polyclonal (aa1-348) (Biotin) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
GALE / UDP-Glucose 4-Epimerase Antibody - Immunohistochemistry of paraffin-embedded human kidney using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GALE / UDP-Glucose 4-Epimerase Rabbit anti-Human Polyclonal (aa1-348) (FITC) Antibody
Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
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GALE / UDP-Glucose 4-Epimerase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$341
GALE / UDP-Glucose 4-Epimerase Antibody - ICC/IF analysis of GALE in Hep3B cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human GALE antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
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GALE / UDP-Glucose 4-Epimerase Mouse anti-Human Monoclonal (AT6G10) Antibody
Human
ELISA, Flo, ICC, WB
Unconjugated
50 µl/$303; 100 µl/$365
GALE / UDP-Glucose 4-Epimerase Antibody - IHC of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-GALE mouse monoclonal antibody.
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GALE / UDP-Glucose 4-Epimerase Mouse anti-Human Monoclonal (OTI1C4) Antibody
Dog, Rat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µl/$434
GALE / UDP-Glucose 4-Epimerase Antibody - IHC of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-GALE mouse monoclonal antibody.
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GALE / UDP-Glucose 4-Epimerase Mouse anti-Human Monoclonal (Carrier-free) (OTI1C4) Antibody
Dog, Rat, Human, Monkey
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
GALE / UDP-Glucose 4-Epimerase Antibody - Immunofluorescence analysis of A549 cells.
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GALE / UDP-Glucose 4-Epimerase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
GALE / UDP-Glucose 4-Epimerase Antibody - Immunofluorescent analysis of GALE staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
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GALE / UDP-Glucose 4-Epimerase Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
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GALE / UDP-Glucose 4-Epimerase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
100 µl/$412
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GALE / UDP-Glucose 4-Epimerase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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GALE / UDP-Glucose 4-Epimerase Rabbit anti-Human Polyclonal (aa142-171) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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GALE / UDP-Glucose 4-Epimerase Rabbit anti-Human Polyclonal (aa142-171) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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GALE / UDP-Glucose 4-Epimerase Rabbit anti-Human Polyclonal (aa142-171) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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GALE / UDP-Glucose 4-Epimerase Rabbit anti-Human Polyclonal (aa142-171) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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GALE / UDP-Glucose 4-Epimerase Rabbit anti-Human Polyclonal (aa142-171) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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GALE / UDP-Glucose 4-Epimerase Rabbit anti-Human Polyclonal (aa142-171) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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GALE / UDP-Glucose 4-Epimerase Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$749
GALE / UDP-Glucose 4-Epimerase Antibody - Western blot analysis of extracts of MCF-7 cells using GALE antibody. The lane on the left was treated with blocking peptide.
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GALE / UDP-Glucose 4-Epimerase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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GALE / UDP-Glucose 4-Epimerase Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
GALE / UDP-Glucose 4-Epimerase Antibody - GALE antibody Western blot of Transfected 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GALE / UDP-Glucose 4-Epimerase Rabbit anti-Human Polyclonal (aa201-250) Antibody
Human
WB
Unconjugated
100 µl/$424
GALE / UDP-Glucose 4-Epimerase Antibody - Fetal liver lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GALE / UDP-Glucose 4-Epimerase Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
Viewing 1-25 of 51 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).