GAK

cyclin G associated kinase

In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the 'cyclin box.' In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5. Two transcript variants encoding different isoforms have been found for this gene.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

GAK (5)

Publications

No (5)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human GAK Protein (Recombinant GST, N-terminus) (aa151-250) - LS-G58641

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human GAK Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67961

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

143 kDa

Price:

20 µg/$1,107

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Human GAK Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81084

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

143 kDa

Price:

20 µg/$215

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Human GAK Protein (Recombinant GST) (Full Length) - LS-G28564

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

68.97 kDa

Price:

10 µg/$479; 25 µg/$670

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GAK Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100501

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

143 kDa

Price:

100 µg/$710

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