GABRA4

gamma-aminobutyric acid (GABA) A receptor, alpha 4

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABA-A receptor subtype. GABA-A receptors are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse. The GABA-A receptor is a multimeric subunit complex. To date six alpha, four beta, and four gamma subunits, plus alternative splicing variants of some of these subunits, have been identified. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor.

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Products

Proteins (3)

Type

Recombinant (3)

Target

GABRA4 (3)

Publications

No (3)

Tag

6His-SUMO, N-terminus (1)

GST (1)

GST, N-terminus (1)

Species

Human (3)

Source

E. coli (1)

Wheat Germ Extract (2)

Purification

Purified (2)

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Human GABRA4 Protein (Recombinant GST, N-terminus) (aa401-500) - LS-G58633

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human GABRA4 Protein (Recombinant 6His-SUMO, N-terminus) (aa36-258) - LS-G56276

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human GABRA4 Protein (Recombinant GST) (Full Length) - LS-G28550

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

88 kDa

Price:

2 µg/$439

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