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GABPA / NRF2

GA binding protein transcription factor, alpha subunit 60kDa

GABPA / NRF2 is one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene.

Gene Name: GA binding protein transcription factor, alpha subunit 60kDa
Synonyms: GABPA, E4TF1A, E4TF1-60, GA-binding protein alpha chain, NRF2A, RCH04A07, GABP subunit alpha, NFT2, NRF2, Transcription factor E4TF1-60
Target Sequences: NM_002040 NP_002031.2 Q06546

Publications (1)

1
Protection by vitamin D against high-glucose-induced damage in retinal pigment epithelial cells. Ali Mohammad Tohari, Mohammad Almarhoun, Reem Hasaballah Alhasani, Lincoln Biswas, Xinzhi Zhou, James Reilly, Zhihong Zeng, Xinhua Shu. Experimental cell research. 2020 July;392:112023. [Full Text Article] [PubMed:32325079] Related Antibodies: LS-C31637.

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GABPA / NRF2 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Serum
1 Plate/$834
GABPA / NRF2 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).