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GABARAP

GABA(A) receptor-associated protein

Ubiquitin-like modifier that plays a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.

Gene Name: GABA(A) receptor-associated protein
Synonyms: GABARAP, ATG8A, MM46, FLC3B, GABARAP-a
Target Sequences: NM_007278 NP_009209.1 O95166

Publications (2)

1
Chronic ethanol and withdrawal differentially modulate lateral/basolateral amygdala paracapsular and local GABAergic synapses. Diaz MR, Christian DT, Anderson NJ, McCool BA. The Journal of pharmacology and experimental therapeutics. 2011 337:162-70. [PubMed:21209156] [PMC:PMC3063746]
2
Induction of autophagy by Imatinib sequesters Bcr-Abl in autophagosomes and down-regulates Bcr-Abl protein. Gafni J, Papanikolaou T, Degiacomo F, Holcomb J, Chen S, Menalled L, Kudwa A, Fitzpatrick J, Miller S, Ramboz S, Tuunanen PI, Lehtimki KK, Yang XW, Park L, Kwak S, Howland D, Park H, Ellerby LM. American journal of hematology. 2013 [PubMed:23440701] Related Antibodies: LS-C166311.

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Products
Antibodies (88)
Primary (88)
GABARAP (88)
Human (79)
Mouse (60)
Rat (28)
Bat (9)
Bovine (9)
Chimpanzee (9)
Dog (9)
Drosophila (3)
Gibbon (9)
Monkey (9)
Pig (9)
Rabbit (9)
Xenopus (9)
Zebrafish (7)
IHC (29)
IHC-P (12)
WB (82)
ELISA (24)
ICC (8)
IF (36)
Peptide-ELISA (2)
rabbit (81)
mouse (7)
IgG (31)
IgG1 (7)
monoclonal mc (7)
polyclonal pc (81)
424CT5.1.6 (6)
AP Conjugated (2)
APC Conjugated (5)
Atto 390 Conjugated (2)
Atto 488 Conjugated (2)
Atto 594 Conjugated (2)
Azide-free (1)
Biotin Conjugated (12)
DY488 Conjugated (2)
DY550 Conjugated (2)
DY650 Conjugated (2)
FITC Conjugated (10)
HRP Conjugated (8)
PE Conjugated (3)
PerCP Conjugated (2)
Preservative Free (1)
RPE Conjugated (2)
Unconjugated (32)
N-Terminus (7)
aa1-30 (7)
C-Terminus (4)
aa21-70 (4)
aa1-50 (1)
aa33-66 (1)
No (87)
Yes (1)
GABARAP Antibody - Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with Autophagy GABARAP Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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GABARAP Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
GABARAP Antibody - Immunohistochemical analysis of GABARAP staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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GABARAP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
GABARAP Antibody - Immunohistochemistry: GABARAP Antibody - Analysis of GABARAP in mouse liver using DAB with hematoxylin counterstain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GABARAP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IHC, IHC-P, WB
Unconjugated
0.1 ml/$386
GABARAP Antibody - Immunohistochemistry: GABARAP Antibody - Analysis of GABARAP in mouse liver using DAB with hematoxylin counterstain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GABARAP Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Human
ICC, IHC, IHC-P, WB
Biotin Conjugated
0.1 ml/$416
GABARAP Antibody - Immunohistochemistry: GABARAP Antibody - Analysis of GABARAP in mouse liver using DAB with hematoxylin counterstain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GABARAP Rabbit anti-Human Polyclonal (DY650) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-P, WB
DY650 Conjugated
0.1 ml/$416
GABARAP Antibody - Immunohistochemistry: GABARAP Antibody - Analysis of GABARAP in mouse liver using DAB with hematoxylin counterstain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GABARAP Rabbit anti-Human Polyclonal (DY488) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-P, WB
DY488 Conjugated
0.1 ml/$416
GABARAP Antibody - Immunohistochemistry: GABARAP Antibody - Analysis of GABARAP in mouse liver using DAB with hematoxylin counterstain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GABARAP Rabbit anti-Human Polyclonal (DY550) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-P, WB
DY550 Conjugated
0.1 ml/$416
GABARAP Antibody - Immunohistochemistry of GABARAP in mouse brain tissue with GABARAP Antibodyat 5 µg/mL.
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GABARAP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
0.1 mg/$460
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GABARAP Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
200 µl/$734
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GABARAP Rabbit anti-Human Polyclonal (aa1-30) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
200 µl/$952
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GABARAP Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Human
ELISA, IF, IHC, WB
Biotin Conjugated
200 µl/$952
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GABARAP Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody
Human
IF, IHC, WB
FITC Conjugated
200 µl/$952
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GABARAP Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody
Human
ELISA, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
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GABARAP Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody
Human
ELISA, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
GABARAP Antibody - Immunohistochemistry of paraffin-embedded rat kidney tissue.
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GABARAP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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GABARAP Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Rat, Human
IF, IHC, WB
Unconjugated
100 µl/$688
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GABARAP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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GABARAP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
GABARAP Antibody - Immunohistochemistry of paraffin-embedded human mammary cancer using GABARAP antibody at dilution of 1:100 (40x lens).
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GABARAP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
GABARAP Antibody - Immunofluorescence staining of HepG2 cells with GABARAP Antibody at 1:93, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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GABARAP Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
GABARAP Antibody - Western blot of Casein kinase II subunit beta antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 13 kDa. Observed band size: 80 kDa.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GABARAP Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
GABARAP Antibody - Western blot of Casein kinase II subunit beta antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 13 kDa. Observed band size: 80 kDa.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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GABARAP Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
GABARAP Antibody - Detection of GABARAP in formalin-fixed human neuroblastoma cell line SK-N-BE with GABARAP Polyclonal Antibody diluted 1:100. DAPI (blue) nuclear stain, Texas red actin stain, and FITC (green) GABARAP stain.
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GABARAP Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
100 µg/$537
GABARAP Antibody - Detection of GABARAP in formalin-fixed human neuroblastoma cell line SK-N-BE with GABARAP Polyclonal Antibody diluted 1:100. DAPI (blue) nuclear stain, Texas red actin stain, and FITC (green) GABARAP stain.
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GABARAP Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
100 µg/$537
GABARAP Antibody - 1:100 staining mouse kidney tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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GABARAP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).