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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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G6PC / Glucose-6-Phosphatase

glucose-6-phosphatase, catalytic subunit

Glucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P, inorganic phosphate, and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Mutations in this gene cause glycogen storage disease type I (GSD1). This disease, also known as von Gierke disease, is a metabolic disorder characterized by severe hypoglycemia associated with the accumulation of glycogen and fat in the liver and kidneys.

Gene Name: glucose-6-phosphatase, catalytic subunit
Synonyms: G6PC, G6Pase-alpha, G6PC1, G-6-Pase, GSD1, Glucose-6-phosphatase alpha, G6Pase, G6PT, Glucose-6-phosphatase, GSD1a
Target Sequences: NM_000151 NP_000142.2 P35575

Publications (1)

1
Elevated hepatic expression of H19 long noncoding RNA contributes to diabetic hyperglycemia. Zhang N, Geng T, Wang Z, Zhang R, Cao T, Camporez JP, Cai SY, Liu Y, Dandolo L, Shulman GI, Carmichael GG, Taylor HS, Huang Y. JCI insight. 2018 May;3:pii: 120304. (Mouse) [Full Text Article] [PubMed:29769440] [PMC:PMC6012507] Related Antibodies: LS-C446262.

Filtered by: None
Target
G6PC / Glucose-6-Phosphatase (17)
Reactivity
Human (17)
Mouse (4)
Rat (3)
Dog (4)
Gibbon (3)
Application
IHC (8)
IHC-P (2)
WB (13)
Flo (7)
ELISA (12)
Host
rabbit (17)
Isotype
IgG (12)
Clonality
polyclonal pc (17)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (5)
Epitope
aa123-149 (8)
N-Terminus (4)
aa82-117 (1)
Publications
No (16)
Yes (1)
Showing 1-17 of 17 results

IHC-plus™ G6PC / Glucose-6-Phosphatase Antibody LS-B15734
Rabbit Polyclonal (IgG) to Human G6PC / Glucose-6-Phosphatase
Human
ELISA, IHC-P
Unconjugated
50µg 1mg/ml  $425.00
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)

G6PC / Glucose-6-Phosphatase Antibody (aa82-117, HRP) LS-C395770
Rabbit Polyclonal (IgG) to Human G6PC / Glucose-6-Phosphatase
Human
ELISA
HRP Conjugated
50µg  $285.00; 100µg 0.42mg/ml  $385.00

G6PC / Glucose-6-Phosphatase Antibody (Biotin) LS-C395771
Rabbit Polyclonal (IgG) to Human G6PC / Glucose-6-Phosphatase
Human
ELISA
Biotin Conjugated
50µg  $285.00; 100µg 0.25mg/ml  $385.00

G6PC / Glucose-6-Phosphatase Antibody (FITC) LS-C395772
Rabbit Polyclonal (IgG) to Human G6PC / Glucose-6-Phosphatase
Human
ELISA
FITC Conjugated
50µg  $285.00; 100µg  $385.00

G6PC / Glucose-6-Phosphatase Antibody (aa123-149) LS-C321504
Rabbit Polyclonal (IgG) to Human G6PC / Glucose-6-Phosphatase
Human
ELISA, Flo, IHC, WB
Unconjugated
200µl  $590.00

G6PC / Glucose-6-Phosphatase Antibody (aa123-149, Biotin) LS-C214450
Rabbit Polyclonal (IgG) to Human G6PC / Glucose-6-Phosphatase
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200µl 0.45mg/ml  $740.00

G6PC / Glucose-6-Phosphatase Antibody (aa123-149, FITC) LS-C214449
Rabbit Polyclonal (IgG) to Human G6PC / Glucose-6-Phosphatase
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200µl  $740.00

G6PC / Glucose-6-Phosphatase Antibody (aa123-149, Azide-free, HRP) LS-C214451
Rabbit Polyclonal (IgG) to Human G6PC / Glucose-6-Phosphatase
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200µl  $740.00

G6PC / Glucose-6-Phosphatase Antibody (aa123-149, APC) LS-C214448
Rabbit Polyclonal (IgG) to Human G6PC / Glucose-6-Phosphatase
Human
ELISA, Flo, IHC, WB
APC Conjugated
200µl  $740.00

G6PC / Glucose-6-Phosphatase Antibody (aa123-149, PE) LS-C214452
Rabbit Polyclonal (IgG) to Human G6PC / Glucose-6-Phosphatase
Human
ELISA, Flo, IHC, WB
PE Conjugated
200µl  $740.00

G6PC / Glucose-6-Phosphatase Antibody (aa123-149, AP) LS-C214446
Rabbit Polyclonal (IgG) to Human G6PC / Glucose-6-Phosphatase
Human
ELISA, Flo, IHC, WB
AP Conjugated
200µl  $740.00

G6PC / Glucose-6-Phosphatase Antibody (aa123-149) LS-C166302
Rabbit Polyclonal to Human G6PC / Glucose-6-Phosphatase
Human
Flo, IHC, IHC-P, WB
Unconjugated
400µl  $325.00
G6PC Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Western blot of G6PC Antibody in K562 cell line lysates (35 ug/lane). G6PC (arrow) was detected using the purified antibody.

G6PC / Glucose-6-Phosphatase Antibody (N-Terminus) LS-C135157
Rabbit Polyclonal to Mouse G6PC / Glucose-6-Phosphatase
Mouse, Dog, Human
WB
Unconjugated
100µl 0.5mg/ml  $385.00
G6PC antibody Western blot of Mouse Intestine lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

G6PC / Glucose-6-Phosphatase Antibody (N-Terminus, HRP) LS-C446262
Publications (1)
Publications (1)
Rabbit Polyclonal to Mouse G6PC / Glucose-6-Phosphatase
Mouse, Dog, Rat, Gibbon, Human
WB
HRP Conjugated
100µl 0.65mg/ml  $405.00
G6PC antibody Western blot of Mouse Intestine lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

G6PC / Glucose-6-Phosphatase Antibody (N-Terminus, Biotin) LS-C446054
Rabbit Polyclonal to Mouse G6PC / Glucose-6-Phosphatase
Mouse, Dog, Rat, Gibbon, Human
WB
Biotin Conjugated
100µl 1mg/ml  $405.00
G6PC antibody Western blot of Mouse Intestine lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

G6PC / Glucose-6-Phosphatase Antibody (N-Terminus, FITC) LS-C446261
Rabbit Polyclonal to Mouse G6PC / Glucose-6-Phosphatase
Mouse, Dog, Rat, Gibbon, Human
WB
FITC Conjugated
100µl 1mg/ml  $405.00
G6PC antibody Western blot of Mouse Intestine lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

G6PC / Glucose-6-Phosphatase Antibody LS-C808925
Rabbit Polyclonal (IgG) to Human G6PC / Glucose-6-Phosphatase
Human
ELISA, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Showing 1-17 of 17 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).