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G3BP1 / G3BP

GTPase activating protein (SH3 domain) binding protein 1

May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.

Gene Name: GTPase activating protein (SH3 domain) binding protein 1
Synonyms: G3BP1, HDH-VIII, G3BP-1, G3BP, GAP binding protein, HDH VIII
Target Sequences: NM_005754 NP_005745.1 Q13283

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Proteins (9)
Over-Expression Lysate (4)
Recombinant (5)
G3BP1 / G3BP (9)
No (9)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (6)
Human (7)
293T Cells (2)
E. coli (1)
HEK 293 Cells (4)
Wheat Germ Extract (2)
Purified (2)
G3BP1 / G3BP Protein
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E. coli
His
50 µg/$411; 250 µg/$985; 10 µg/$276
G3BP1 / G3BP Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
G3BP1 / G3BP Protein - Purified recombinant protein G3BP1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
52 kDa
20 µg/$1,107
G3BP1 / G3BP Protein - Purified recombinant protein G3BP1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
52 kDa
20 µg/$1,107
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293T Cells
Myc-DDK (Flag)
52 kDa
20 µg/$150
G3BP1 / G3BP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
52 kDa
20 µg/$150
G3BP1 / G3BP Protein - 12.5% SDS-PAGE of human G3BP stained with Coomassie Blue
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Wheat Germ Extract
GST
78.6 kDa
10 µg/$479; 25 µg/$670
G3BP1 / G3BP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
52 kDa
100 µg/$494
G3BP1 / G3BP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
52 kDa
100 µg/$494
Viewing 1-9 of 9 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).