FZD7 / Frizzled 7

frizzled class receptor 7

Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

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Products

Proteins (2)

Type

Recombinant (2)

Target

FZD7 / Frizzled 7 (2)

Publications

No (2)

Tag

GST (1)

GST, N-terminus (1)

Species

Human (2)

Source

Wheat Germ Extract (2)

Purification

Purified (1)

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Human FZD7 / Frizzled 7 Protein (Recombinant GST, N-terminus) (aa155-253) - LS-G60690

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human FZD7 / Frizzled 7 Protein (Recombinant GST) (Full Length) - LS-G31107

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

88.77 kDa

Price:

2 µg/$439

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