FZD5 / Frizzled 5

frizzled class receptor 5

Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Interacts specifically with Wnt5A to induce the beta-catenin pathway.

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Proteins (7)

Type

Over-Expression Lysate (2)

Recombinant (5)

Target

FZD5 / Frizzled 5 (7)

Publications

No (7)

Tag

Fc (1)

GST (1)

GST, N-terminus (1)

His (1)

Human IgG1 Fc (1)

Myc-DDK (Flag) (2)

Species

Human (5)

Mouse (1)

Source

293T Cells (1)

CHO Cells (1)

HEK 293 Cells (2)

Human Cells (1)

Wheat Germ Extract (2)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (3)

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Human FZD5 / Frizzled 5 Protein (Recombinant GST, N-terminus) (aa72-161) - LS-G60616

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human FZD5 / Frizzled 5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81577

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

64.51 kDa

Price:

20 µg/$215

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Human FZD5 / Frizzled 5 Protein (Recombinant His) (Met1-Pro167) - LS-G97485

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

17.6 kDa

Price:

100 µg/$843

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Human FZD5 / Frizzled 5 Protein (Recombinant GST) (Full Length) - LS-G31018

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

90.9 kDa

Price:

2 µg/$439

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FZD5 / Frizzled 5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100060

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

64.51 kDa

Price:

100 µg/$710

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Human FZD5 / Frizzled 5 Protein (Recombinant Human IgG1 Fc) - LS-G3964

Source:

HEK 293 Cells

Tag:

Human IgG1 Fc

Endotoxin Level:

Less than 0.01 EU/µg protein (determined by LAL method).

Molecular Weight:

~50kDa (SDS-PAGE)

Price:

50 µg/$379

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Mouse FZD5 / Frizzled 5 Protein (Recombinant Fc) (Met1-Pro167) - LS-G98160

Source:

CHO Cells

Tag:

Fc

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

42.9 kDa

Price:

100 µg/$926

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