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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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FZD5 / Frizzled 5

frizzled class receptor 5

Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Interacts specifically with Wnt5A to induce the beta-catenin pathway.

Gene Name: frizzled class receptor 5
Family/Subfamily: GPCR , Frizzled
Synonyms: FZD5, C2orf31, DKFZP434E2135, Frizzled family receptor 5, Fz5, Fzd-5, FzE5, Frizzled 5, Frizzled-5, Wnt receptor, Fz-5, HFZ5
Target Sequences: NM_003468 NP_003459.2 Q13467

Publications (1)

1
RAL GTPases Drive Intestinal Stem Cell Function and Regeneration through Internalization of WNT Signalosomes. Johansson J, Naszai M, Hodder MC, Pickering KA, Miller BW, Ridgway RA, Yu Y, Peschard P, Brachmann S, Campbell AD, Cordero JB, Sansom OJ. Cell stem cell. 2019 April;24:592-607. [Full Text Article] [PubMed:30853556] [PMC:PMC6459002] Related Antibodies: LS-A4273.

Viewing 1-25 of 68 items
FZD5 / Frizzled 5 Antibody - Anti-FZD5 / Frizzled 5 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Cancer
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Rabbit Polyclonal to Human FZD5 / Frizzled 5
Mouse, Rat, Hamster, Human
IHC, IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
FZD5 / Frizzled 5 Antibody - Anti-FZD5 / Frizzled 5 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Mouse, Rat, Hamster, Human
IHC, IHC-P
Biotin Conjugated
100µl   $650.00
FZD5 / Frizzled 5 Antibody - Anti-FZD5 / Frizzled 5 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Mouse, Rat, Hamster, Human
IHC, IHC-P
FITC Conjugated
100µl   $650.00
FZD5 / Frizzled 5 Antibody - Anti-FZD5 / Frizzled 5 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Mouse, Rat, Hamster, Human
IHC, IHC-P
HRP Conjugated, Azide-free
100µl   $650.00
FZD5 / Frizzled 5 Antibody - Anti-FZD5 / Frizzled 5 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Mouse, Rat, Hamster, Human
IHC, IHC-P
APC Conjugated
100µl   $650.00
FZD5 / Frizzled 5 Antibody - Anti-FZD5 / Frizzled 5 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Mouse, Rat, Hamster, Human
IHC, IHC-P
AP Conjugated
100µl   $650.00
FZD5 / Frizzled 5 Antibody - Anti-FZD5 / Frizzled 5 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Mouse, Rat, Hamster, Human
IHC, IHC-P
PE Conjugated
100µl   $650.00
FZD5 / Frizzled 5 Antibody - Anti-FZD5 / Frizzled 5 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Cancer
Fast Shipping
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Human
IHC, IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
FZD5 / Frizzled 5 Antibody - Anti-FZD5 / Frizzled 5 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Human
IHC, IHC-P
Biotin Conjugated
100µl   $650.00
FZD5 / Frizzled 5 Antibody - Anti-FZD5 / Frizzled 5 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Human
IHC, IHC-P
FITC Conjugated
100µl   $650.00
FZD5 / Frizzled 5 Antibody - Anti-FZD5 / Frizzled 5 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Human
IHC, IHC-P
AP Conjugated
100µl   $650.00
FZD5 / Frizzled 5 Antibody - Anti-FZD5 / Frizzled 5 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Human
IHC, IHC-P
APC Conjugated
100µl   $650.00
FZD5 / Frizzled 5 Antibody - Anti-FZD5 / Frizzled 5 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Human
IHC, IHC-P
HRP Conjugated, Azide-free
100µl   $650.00
FZD5 / Frizzled 5 Antibody - Anti-FZD5 / Frizzled 5 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Human
IHC, IHC-P
PE Conjugated
100µl   $650.00
FZD5 / Frizzled 5 Antibody - Anti-FZD5 / Frizzled 5 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Rabbit, Dog, Bovine, Pig, Human, Monkey
ELISA, IHC, IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
FZD5 / Frizzled 5 Antibody - Anti-FZD5 / Frizzled 5 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Rabbit, Dog, Bovine, Pig, Human, Monkey
ELISA, IHC, IHC-P
Biotin Conjugated
100µl   $650.00
FZD5 / Frizzled 5 Antibody - Anti-FZD5 / Frizzled 5 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Rabbit, Dog, Bovine, Pig, Human, Monkey
ELISA, IHC, IHC-P
FITC Conjugated
100µl   $650.00
FZD5 / Frizzled 5 Antibody - Anti-FZD5 / Frizzled 5 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Rabbit, Dog, Bovine, Pig, Human, Monkey
ELISA, IHC, IHC-P
PE Conjugated
100µl   $650.00
FZD5 / Frizzled 5 Antibody - Anti-FZD5 / Frizzled 5 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Rabbit, Dog, Bovine, Pig, Human, Monkey
ELISA, IHC, IHC-P
AP Conjugated
100µl   $650.00
FZD5 / Frizzled 5 Antibody - Anti-FZD5 / Frizzled 5 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Rabbit, Dog, Bovine, Pig, Human, Monkey
ELISA, IHC, IHC-P
APC Conjugated
100µl   $650.00
FZD5 / Frizzled 5 Antibody - Anti-FZD5 / Frizzled 5 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human FZD5 / Frizzled 5
Rabbit, Dog, Bovine, Pig, Human, Monkey
ELISA, IHC, IHC-P
HRP Conjugated, Azide-free
100µl   $650.00
FZD5 / Frizzled 5 Antibody - Anti-FZD5 / Frizzled 5 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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Rabbit Polyclonal (IgG) to Human FZD5 / Frizzled 5
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $425.00
FZD5 / Frizzled 5 Antibody - Anti-FZD5 / Frizzled 5 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal to Human FZD5 / Frizzled 5
Mouse, Bovine, Rat, Human
IHC, IHC-P, WB
Unconjugated
100µl   $485.00
FZD5 / Frizzled 5 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Rabbit Polyclonal (IgG) to Human FZD5 / Frizzled 5
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
100µl   1mg/ml   $505.00
FZD5 / Frizzled 5 Antibody - A: Marker, B: HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal (IgG) to Human FZD5 / Frizzled 5
Mouse, Human
WB
Unconjugated
100µl   0.5mg/ml   $385.00

Viewing 1-25 of 68 items


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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).