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We could not find product '(ID:1347)'. Here are some alternate products to this target that might be of interest to you.
FZD2 / Frizzled 2
frizzled class receptor 2
Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
| Gene Name: | frizzled class receptor 2 |
| Family/Subfamily: | GPCR , Frizzled |
| Synonyms: | FZD2, Dfrizzled2, Fz2, Frizzled family receptor 2, Frizzled-2, HFz2, Frizzled homolog 2, Fz-2, FzE2, Mfz10, Rfz2, Frizzled 2 |
| Target Sequences: | NM_001466 NP_001457.1 Q14332 |
Publications (1)
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