FZD1 / Frizzled 1

frizzled class receptor 1

Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Activated by Wnt3A, Wnt3, Wnt1 and to a lesser extent Wnt2, but not by Wnt4, Wnt5A, Wnt5B, Wnt6, Wnt7A or Wnt7B.

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Products

ELISA Kits (7)

Type

Custom (3)

Sandwich (3)

Sandwich CLIA (1)

Target

FZD1 / Frizzled 1 (7)

Reactivity

Human (4)

Mouse (1)

Rat (1)

Chicken (1)

Format

96-Well Strip Plate (7)

Publications

No (7)

Sample Type

Plasma (3)

Serum (3)

Tissue Homogenates (3)

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Human FZD1 / Frizzled 1 (CLIA) ELISA Kit - LS-F38872

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.14 - 100 ng/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$968

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Rat FZD1 / Frizzled 1 (Custom ELISA) ELISA Kit - LS-F16048

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Chicken FZD1 / Frizzled 1 (Custom ELISA) ELISA Kit - LS-F16049

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Chicken

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$929

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Mouse FZD1 / Frizzled 1 (Custom ELISA) ELISA Kit - LS-F16050

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Human FZD1 / Frizzled 1 (Sandwich ELISA) ELISA Kit - LS-F11499

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Human FZD1 / Frizzled 1 (Sandwich ELISA) ELISA Kit - LS-F34051

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human FZD1 / Frizzled 1 (Sandwich ELISA) ELISA Kit - LS-F8285

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Tissue Homogenates

Price:

1 Plate/$834

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