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FXR2

fragile X mental retardation, autosomal homolog 2

FXR2 is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome.

Gene Name: fragile X mental retardation, autosomal homolog 2
Synonyms: FXR2, FXR2P, FMR1L2
Target Sequences: NM_004860

Publications (1)

1
Discrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs. Darnell JC, Fraser CE, Mostovetsky O, Darnell RB. Human molecular genetics. 2009 18:3164-77. [PubMed:19487368] [PMC:PMC2722981]

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).