FXN / Frataxin

frataxin

Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+; the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization; however, the physiological relevance is unsure as reports are conflicting and the function has only been shown using heterologous overexpression systems. Modulates the RNA-binding activity of ACO1.

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Products

Proteins (18)

Type

Over-Expression Lysate (4)

Recombinant (14)

Target

FXN / Frataxin (18)

Publications

No (16)

Yes (2)

Tag

10His, N-terminus (1)

10His, N-terminus + Myc, C-terminus (1)

10His-SUMO, N-terminus + Myc, C-terminus (1)

6His, N-terminus (4)

GST (1)

GST, N-terminus (1)

His (1)

His-SUMO (1)

His-T7 (1)

Myc-DDK (Flag) (5)

Species

Cynomolgus monkey (1)

Human (10)

Mouse (4)

Rat (2)

Source

293T Cells (2)

E. coli (10)

HEK 293 Cells (3)

Wheat Germ Extract (2)

Yeast (1)

Purification

Purified (7)

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Cynomolgus monkey FXN / Frataxin Protein (Recombinant 6His, N-terminus) (aa81-210) - LS-G21788

(4.0) Rating

(1) Publication(s)

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

18.3 kD

Price:

100 µg/$598; 20 µg/$405; 1 mg/$1,679

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Human FXN / Frataxin Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68166

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18.8 kDa

Price:

20 µg/$1,107

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Human FXN / Frataxin Protein (Recombinant His) - LS-G669

Source:

E. coli

Tag:

His

Price:

100 µg/$411; 500 µg/$985; 20 µg/$276

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Mouse FXN / Frataxin Protein (Recombinant 6His, N-terminus) (aa78-207) - LS-G22926

Source:

Yeast

Tag:

6His, N-terminus

Molecular Weight:

16.4 kD

Price:

1 mg/$1,683; 100 µg/$499; 20 µg/$364

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Mouse FXN / Frataxin Protein (Recombinant 6His, N-terminus) (aa41-207) - LS-G14956

(4.0) Rating

(1) Publication(s)

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

22.4 kDa

Price:

10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090

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Mouse FXN / Frataxin Protein (Recombinant 6His, N-terminus) (Full Length) - LS-G137019

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

19.9 kDa

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Human FXN / Frataxin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G127894

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

19.09 kDa

Price:

100 µg/$494

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Human FXN / Frataxin Protein (Recombinant GST) (Full Length) - LS-G28513

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

49.5 kDa

Price:

10 µg/$479; 25 µg/$670

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Mouse FXN / Frataxin Protein (Recombinant His-SUMO) (aa78-207) - LS-G20748

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

30.4 kD

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Human FXN / Frataxin Protein (Recombinant GST, N-terminus) (aa91-200) - LS-G58607

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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FXN / Frataxin Protein (Recombinant 10His, N-terminus) (aa41-208) - LS-G56274

Source:

E. coli

Tag:

10His, N-terminus

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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FXN / Frataxin Protein (Recombinant) (aa41-208) - LS-G56277

Source:

E. coli

Tag:

None

Price:

1 mg/$1,756; 100 µg/$611; 20 µg/$447

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Human FXN / Frataxin Protein (Recombinant 10His, N-terminus + Myc, C-terminus) (Full Length) - LS-G56696

Source:

E. coli

Tag:

10His, N-terminus + Myc, C-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human FXN / Frataxin Protein (Recombinant 10His-SUMO, N-terminus + Myc, C-terminus) (aa1-210) - LS-G56697

Source:

E. coli

Tag:

10His-SUMO, N-terminus + Myc, C-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human FXN / Frataxin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81587

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

19.09 kDa

Price:

20 µg/$150

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Human FXN / Frataxin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81588

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

23.14 kDa

Price:

20 µg/$150

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FXN / Frataxin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G98938

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

23.14 kDa

Price:

100 µg/$494

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Human FXN / Frataxin Protein (Recombinant His-T7) (aa57-198) - LS-G14951

Source:

E. coli

Tag:

His-T7

Molecular Weight:

19.8 kDa

Price:

10 µg/$273; 50 µg/$392; 100 µg/$625; 200 µg/$782; 1 mg/$1,847; 500 µg/$1,404; 5 mg/$2,807; 2 mg/$2,029

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