Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

FTL / Ferritin Light Chain

ferritin, light polypeptide

FTL / Ferritin Light Chain is the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes.

Gene Name: ferritin, light polypeptide
Synonyms: FTL, Ferritin L subunit, Ferritin L-chain, Ferritin, light polypeptide, Ferritin light chain, NBIA3
Target Sequences: NM_000146 NP_000137.2 P02792

Publications (3)

1
Ferritin in glioblastoma. Heidi Jaksch-Bogensperger , Sabine Spiegl-Kreinecker, Paolo Arosio, Peter Eckl, Stefan Golaszewski, Yvonne Ebner, Rahman Al-Schameri, Peter Strasser, Serge Weis , Nikolaus Bresgen. British journal of cancer. 2020 May;122:1441-1444. [Full Text Article] [PubMed:32203223] [PMC:PMC7217840] Related Antibodies: LS-B4383.
2
Multitissue analysis of exercise and metformin on doxorubicin-induced iron dysregulation. Amy D Mackay, Erik D Marchant, Devin J Munk, Richard K Watt, Jason M Hansen, David M Thomson, Chad R Hancock. American journal of physiology. Endocrinology and metabolism. 2019 May;316:E922-E930. [Full Text Article] [PubMed:30888858]
3
Unbalance in Iron Metabolism in Childhood Leukemia Converges with Treatment Intensity: Biochemical and Clinical Analysis. Monika Lecka, Artur Slomka, Katarzyna Albrecht, Ewa Zekanowska, Michal Romiszewski, Jan Styczynski. Cancers. 2021 June;13:3029. [Full Text Article] [PubMed:34204310] [PMC:PMC8233795]

Your search did not match any products.


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).