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FSH Receptor / FSHR

follicle stimulating hormone receptor

FSHR, a Glycoprotein Hormone Receptor, is required for normal ovarian development and follicle maturation in females. When activated, it stimulates ovarian follicular growth and production of estrogens, initiating a normal menstrual cycle. In males, FSHR is required for the initiation of spermatogenesis and normal sperm production. Two isoforms are produced by alternative splicing.

Gene Name:	follicle stimulating hormone receptor
Family/Subfamily:	GPCR , Glycoprotein hormone
Synonyms:	FSHR, FSHRO, Ovarian dysgenesis 1, FSH receptor, FSH-R, LGR1, ODG1
Target Sequences:	NM_000145 NP_000136.2 P23945

Publications (2)

Effect of stallion age on the expression of LH and FSH receptors and aromatase P450 in equine male reproductive tissues. Herrera-Luna CV, Scarlet D, Walter I, Aurich C. Reproduction, fertility, and development. 2016 28:2016-2026. (WB, IHC-P; Human) [Full Text Article] [PubMed:26143654]

Exposure to N-monoacetyl-p-phenylenediamine impaired ovarian function in mice. Liliang Yu, Jingwei Zhai, Yingxiong Wang, Yanqing Geng, Xuemei Chen, Yixian Wen, Hongyu Tang, Rao Yu, Yue Zhang, Xueqing Liu. Journal of applied toxicology : JAT. 2021 December;41:2031-2041. [Full Text Article] [PubMed:34014586] Related Antibodies: LS-C332397.

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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