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Shirley, MA 01464
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FSCN2 / Retinal Fascin
fascin actin-bundling protein 2, retinal
FSCN2 / Retinal Fascin is a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | fascin actin-bundling protein 2, retinal |
| Synonyms: | FSCN2, Fascin-2, Retinal fascin, RP30, RFSN |
| Target Sequences: | NM_012418 NP_036550.1 O14926 |
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