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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.
TCR Screening ServicesTest your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
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FRS2
fibroblast growth factor receptor substrate 2
Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
| Gene Name: | fibroblast growth factor receptor substrate 2 |
| Synonyms: | FRS2, FGFR substrate 2, FRS2A, FGFR signalling adaptor, FGFR-signaling adaptor SNT, FRS2alpha, SNT-1, SNT1, SNT |
| Target Sequences: | NM_006654 NP_006645.3 Q8WU20 |
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