FREM1

FRAS1 related extracellular matrix 1

FREM1 is a basement membrane protein that may play a role in craniofacial and renal development. Mutations in this gene have been associated with bifid nose with or without anorectal and renal anomalies. Alternatively spliced transcript variants encoding different isoforms have been described. PubMed ID 19940113 describes one such variant that initiates transcription within a distinct, internal exon; the resulting shorter isoform (named Toll-like/interleukin-1 receptor regulator, TILRR) is suggested to be a co-receptor of the interleukin 1 receptor family and may regulate receptor function and Toll-like receptor/interleukin 1 receptor signal transduction, contributing to the control of inflammatory response activation.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

FREM1 (3)

Publications

No (3)

Tag

Myc-DDK (Flag) (3)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (2)

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Human FREM1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72513

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

241.9 kDa

Price:

20 µg/$1,107

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FREM1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102298

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

241.9 kDa

Price:

100 µg/$710

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Human FREM1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G92688

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

241.9 kDa

Price:

20 µg/$215

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