FPGT

Fucose-1-phosphate Guanylyltransferase

L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules, such as in cell-cell recognition. The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose. There are two alternate pathways for the biosynthesis of GDP-fucose; the major pathway converts GDP-alpha-D-mannose to GDP-beta-L-fucose. The protein encoded by this gene participates in an alternate pathway that is present in certain mammalian tissues, such as liver and kidney, and appears to function as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids. This pathway involves the phosphorylation of L-fucose to form beta-L-fucose-1-phosphate, and then condensation of the beta-L-fucose-1-phosphate with GTP by fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream TNNI3 interacting kinase (TNNI3K) gene.

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Products

Proteins (7)

Type

Over-Expression Lysate (2)

Recombinant (5)

Target

FPGT (7)

Publications

No (7)

Tag

GST (1)

GST, N-terminus (1)

His (1)

His-T7, N-terminus (2)

Myc-DDK (Flag) (2)

Species

Human (5)

Mouse (1)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Yeast (1)

Purification

Purified (2)

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Human FPGT Protein (Recombinant His-T7, N-terminus) (Leu127-Ser377) - LS-G133339

Source:

E. coli

Tag:

His-T7, N-terminus

Molecular Weight:

32.3kDa

Price:

10 µg/$271; 50 µg/$375; 200 µg/$750; 100 µg/$600; 1 mg/$1,797; 500 µg/$1,362; 5 mg/$2,755; 2 mg/$1,979

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Human FPGT Protein (Recombinant GST) (Full Length) - LS-G31329

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

93 kDa

Price:

10 µg/$479; 25 µg/$670

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FPGT Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117055

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

66.4 kDa

Price:

100 µg/$494

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Human FPGT Protein (Recombinant His) (Full Length) - LS-G22925

Source:

Yeast

Tag:

His

Molecular Weight:

68.6 kD

Price:

100 µg/$446; 20 µg/$336; 1 mg/$1,460

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Human FPGT Protein (Recombinant GST, N-terminus) (aa1-109) - LS-G60864

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human FPGT Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80262

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

66.4 kDa

Price:

20 µg/$150

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Mouse FPGT Protein (Recombinant His-T7, N-terminus) (His314-Leu513) - LS-G133478

Source:

E. coli

Tag:

His-T7, N-terminus

Molecular Weight:

25.6kDa

Price:

10 µg/$275; 50 µg/$405; 200 µg/$810; 100 µg/$647; 1 mg/$1,887; 500 µg/$1,440; 5 mg/$2,851; 2 mg/$2,072

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