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FOXE3

forkhead box E3

This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. The protein encoded functions as a lens-specific transcription factor and plays an important role in vertebrate lens formation. Mutations in this gene are associated with anterior segment mesenchymal dysgenesis and congenital primary aphakia.

Gene Name: forkhead box E3
Family/Subfamily: Transcription factor , not assigned-Transcription factor
Synonyms: FOXE3, ASMD, FKHL12, Forkhead box E3, Forkhead box protein E3, Forkhead protein 8, FREAC-8, FREAC8
Target Sequences: NM_012186 NP_036318.1 Q13461

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).