Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

FOXD3

forkhead box D3

Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis.

Gene Name: forkhead box D3
Family/Subfamily: Transcription factor , not assigned-Transcription factor
Synonyms: FOXD3, AIS1, Drosophila forkhead homologue, Genesis, Forkhead box protein D3, Forkhead box D3, HFH2, VAMAS2
Target Sequences: NM_012183 NP_036315.1 Q9UJU5

Publications (2)

1
FOXD3 is a mutant B-RAF-regulated inhibitor of G(1)-S progression in melanoma cells. Abel EV, Aplin AE. Cancer research. 2010 70:2891-900. [PubMed:20332228] [PMC:PMC2848900]
2
FOXD3 regulates migration properties and Rnd3 expression in melanoma cells. Katiyar P, Aplin AE. Molecular cancer research : MCR. 2011 9:545-52. [PubMed:21478267] [PMC:PMC3096755]

Your search did not match any products.


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).