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FOLR1 / Folate Receptor Alpha
folate receptor 1 (adult)
Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation.
| Gene Name: | folate receptor 1 (adult) |
| Synonyms: | FOLR1, Adult folate-binding protein, FBP, Folate receptor alpha, KB cells FBP, Folate binding protein, Folate receptor 1, Folate receptor 1 (adult), Folate receptor, adult, FOLR, FR-alpha |
| Target Sequences: | NM_016730 NP_057942.1 P15328 |
Publications (6)
1
A folate receptor-targeted lipoplex delivering interleukin-15 gene for colon cancer immunotherapy. Liang X, Luo M, Wei XW, Ma CC, Yang YH, Shao B, Liu YT, Liu T, Ren J, Liu L, He ZY, Wei YQ. Oncotarget. 2016 7:52207-52217. (Flo; Mouse)
[Full Text Article]
[PubMed:27438147]
[PMC:PMC5239545]
Related Antibodies: LS-B5727.
2
Expression status of folate receptor alpha is a predictor of survival in pancreatic ductal adenocarcinoma. Cai L, Michelakos T, Ferrone CR, Zhang L, Deshpande V, Shen Q, DeLeo A, Yamada T, Zhang G, Ferrone S, Wang X. Oncotarget. 2017 8:37646-37656. (IHC, Flo; Human)
[Full Text Article]
[PubMed:28430580]
[PMC:PMC5514937]
Related Antibodies: LS-B5727, LS-C129132.
3
Intraoperative near-infrared fluorescence imaging targeting folate receptors identifies lung cancer in a large-animal model. Keating JJ, Runge JJ, Singhal S, Nims S, Venegas O, Durham AC, Swain G, Nie S, Low PS, Holt DE. Cancer. 2017 May;123:1051-1060. [Full Text Article]
[PubMed:28263385]
[PMC:PMC5341137]
Related Antibodies: LS-B5727.
☰ Filters
Products
Proteins
(21)
Type
Over-Expression Lysate
(10)
Recombinant
(11)
Target
FOLR1 / Folate Receptor Alpha
(21)
Publications
No
(21)
Tag
6His, C-terminus
(2)
AVI-6His, C-terminus
(1)
Fc
(1)
GST
(1)
His
(4)
His, C-Terminal
(1)
His,C-terminus
(1)
Myc-DDK (Flag)
(10)
Species
Human
(11)
Mouse
(3)
Rat
(2)
Source
293T Cells
(5)
E. coli
(3)
HEK 293 Cells
(5)
Human
(2)
Human Cells
(3)
Mammalian Cells
(2)
Wheat Germ Extract
(1)
Purification
Purified
(4)
Low Endotoxin Level
Low endotoxin level
(7)
E. coli
His
25.9 kDa
10 µg/$263; 50 µg/$341; 100 µg/$522; 200 µg/$652; 1 mg/$1,643; 500 µg/$1,230; 5 mg/$2,585; 2 mg/$1,817
E. coli
His
25.4 kDa
10 µg/$269; 50 µg/$370; 100 µg/$590; 200 µg/$737; 1 mg/$1,779; 500 µg/$1,345; 5 mg/$2,736; 2 mg/$1,959
HEK 293 Cells
Myc-DDK (Flag)
29.82 kDa
100 µg/$494
HEK 293 Cells
Myc-DDK (Flag)
29.82 kDa
100 µg/$494
HEK 293 Cells
Myc-DDK (Flag)
29.82 kDa
100 µg/$494
HEK 293 Cells
Myc-DDK (Flag)
29.82 kDa
100 µg/$494
Human
AVI-6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
27.5 kDa
20 µg/$416; 100 µg/$910
Wheat Germ Extract
GST
54.01 kDa
2 µg/$439
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
293T Cells
Myc-DDK (Flag)
29.82 kDa
20 µg/$150
293T Cells
Myc-DDK (Flag)
29.82 kDa
20 µg/$150
293T Cells
Myc-DDK (Flag)
29.82 kDa
20 µg/$150
293T Cells
Myc-DDK (Flag)
29.82 kDa
20 µg/$150
293T Cells
Myc-DDK (Flag)
29.82 kDa
20 µg/$150
HEK 293 Cells
Myc-DDK (Flag)
29.82 kDa
100 µg/$494
Human Cells
Fc
Less than 1.0 EU/µg protein (determined by LAL method).
50.9 kDa
50 µg/$483
Mouse FOLR1 / Folate Receptor Alpha Protein (Recombinant His, C-Terminal) (Thr25-Ser232) - LS-G55676
Human
His, C-Terminal
Less than 1.0 EU/µg protein (determined by LAL method).
25.3kD
10 µg/$266; 50 µg/$376; 500 µg/$1,067; 1 mg/$1,369
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
25.6 kDa
100 µg/$721
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
25.7kD
10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157
Mouse FOLR1 / Folate Receptor Alpha Protein (Recombinant His,C-terminus) (Thr25-Ser232) - LS-G139026
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
25.3 kDa
10 µg/$266; 50 µg/$371
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
25.7 kDa
10 µg/$281; 50 µg/$389
Viewing 1-21
of 21
product results
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