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FN1 / Fibronectin

fibronectin 1

Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts.Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.

Gene Name: fibronectin 1
Synonyms: FN1, CIG, Cold-insoluble globulin, Fibronectin 1, FINC, LETS, GFND, ED-B, Fibronectin, FN, FNZ, GFND2, Migration-stimulating factor, MSF
Target Sequences: NM_002026 NP_002017.1 P02751

Publications (4)

1
Structural and Functional Characterization of Fibronectin in Extracellular Vesicles From Hepatocytes. Xinlei Li, Ruju Chen, Sherri Kemper, David R Brigstock. Frontiers in cell and developmental biology. 2021 Mar;9:640667. [Full Text Article] [PubMed:33816490] [PMC:PMC8012540]
2
Interventricular Differences of Signaling Pathways-Mediated Regulation of Cardiomyocyte Function in Response to High Oxidative Stress in the Post-Ischemic Failing Rat Heart. Árpád Kovács , Melissa Herwig , Heidi Budde , Simin Delalat , Detmar Kolijn , Beáta Bódi, Roua Hassoun , Melina Tangos , Saltanat Zhazykbayeva , Ágnes Balogh, Dániel Czuriga, Sophie Van Linthout, Carsten Tschöpe, Naranjan S Dhalla, Andreas Mügge , Attila Tóth , Zoltán Papp , Judit Barta, Nazha Hamdani. Antioxidants. 2021 Jun;10:964. [Full Text Article] [PubMed:34208541] [PMC:PMC8234177]
3
Long-Term Dipeptidyl Peptidase 4 Inhibition Worsens Hypertension and Renal and Cardiac Abnormalities in Obese Spontaneously Hypertensive Heart Failure Rats. Edwin K Jackson, Zaichuan Mi, Delbert G Gillespie, Dongmei Cheng, Stevan P Tofovic. Journal of the American Heart Association. 2021 March;10:e020088. [Full Text Article] [PubMed:33682436] [PMC:PMC8174220]
4
Decellularization alters the unfavorable regenerative adverse microenvironment of the injured spinal cord to support neurite outgrowth. Junxia Hu , Jianghong Shangguan , Parizat Askar, Jinghui Xu, Hualin Sun, Songlin Zhou, Changlai Zhu, Wenfeng Su, Yun Gu. Annals of translational medicine. 2022 September;10:934. [Full Text Article] [PubMed:36172103] [PMC:PMC9511201] Related Antibodies: LS-C85816.
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FN1 / Fibronectin ELISA Kit
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Sandwich
96-Well Microplate
Mouse
156 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$795
FN1 / Fibronectin ELISA Kit
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96-Well Strip Plate
Rat
156 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$717
FN1 / Fibronectin ELISA Kit
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Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$585
FN1 / Fibronectin ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$782
FN1 / Fibronectin ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$719
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Sandwich
96-Well Strip Plate
Porcine
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$863
FN1 / Fibronectin ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$818
FN1 / Fibronectin ELISA Kit
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Sandwich
96-Well Microplate
Rat
156 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$795
FN1 / Fibronectin ELISA Kit
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Sandwich
96-Well Strip Plate
Human
156 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$717
FN1 / Fibronectin ELISA Kit
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Sandwich CLIA
96-Well Strip Plate
Human
0.27 - 200 ng/ml
Chemiluminescent
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$968
FN1 / Fibronectin ELISA Kit
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Sandwich
96-Well Microplate
Human
0.614 - 150 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$700
FN1 / Fibronectin ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Human
0.313 - 20 ng/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
FN1 / Fibronectin ELISA Kit
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Sandwich
96-Well Microplate
Rat
1.25 - 80 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
FN1 / Fibronectin ELISA Kit
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Sandwich
96-Well Strip Plate
Human
15.625 - 1000 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
FN1 / Fibronectin ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
FN1 / Fibronectin ELISA Kit
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Sandwich
96-Well Strip Plate
Bovine
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
FN1 / Fibronectin ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
12.5 - 800 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
FN1 / Fibronectin ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
FN1 / Fibronectin ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
12.5 - 800 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
FN1 / Fibronectin ELISA Kit
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Sandwich
96-Well Strip Plate
Human
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$579
FN1 / Fibronectin ELISA Kit
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Development Kit
Antibody Pair and Standard
Rabbit
3.12 - 200 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
500 Wells/$1,159; 1000 Wells/$1,707
FN1 / Fibronectin ELISA Kit
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Sandwich
96-Well Microplate
Human
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
FN1 / Fibronectin ELISA Kit
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Sandwich
96-Well Microplate
Mouse
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
FN1 / Fibronectin ELISA Kit
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Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
FN1 / Fibronectin ELISA Kit
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Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).