FLT1 / VEGFR1

fms-related tyrosine kinase 1

Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. May play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. Can promote endothelial cell proliferation, survival and angiogenesis in adulthood. Its function in promoting cell proliferation seems to be cell-type specific. Promotes PGF-mediated proliferation of endothelial cells, proliferation of some types of cancer cells, but does not promote proliferation of normal fibroblasts (in vitro). Has very high affinity for VEGFA and relatively low protein kinase activity; may function as a negative regulator of VEGFA signaling by limiting the amount of free VEGFA and preventing its binding to KDR. Likewise, isoforms lacking a transmembrane domain, such as isoform 2, isoform 3 and isoform 4, may function as decoy receptors for VEGFA. Modulates KDR signaling by forming heterodimers with KDR. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate and the activation of protein kinase C. Mediates phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, leading to activation of phosphatidylinositol kinase and the downstream signaling pathway. Mediates activation of MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Phosphorylates SRC and YES1, and may also phosphorylate CBL. Isoform 1 phosphorylates PLCG. Promotes phosphorylation of AKT1 at 'Ser-473'. Promotes phosphorylation of PTK2/FAK1. Isoform 7 has a truncated kinase domain; it increases phosphorylation of SRC at 'Tyr-418' by unknown means and promotes tumor cell invasion.

☰ Filters

Products

ELISA Kits (38)

Type

Custom (1)

Sandwich (32)

Sandwich CLIA (5)

Target

FLT1 / VEGFR1 (38)

Reactivity

Human (13)

Mouse (10)

Rat (6)

Chicken (2)

Guinea pig (1)

Pig (2)

Porcine (1)

Rabbit (1)

Sheep (2)

Format

12 x 8-Well Microstrips (4)

96-Well Microplate (7)

96-Well Strip Plate (27)

Publications

No (37)

Yes (1)

Sample Type

Cell Culture Supernatants (5)

Cell Lysates (4)

Follicular Fluid (3)

Plasma (32)

Saliva (3)

Serum (33)

Tissue Homogenates (12)

Select

Rat FLT1 / VEGFR1 (Sandwich ELISA) ELISA Kit - LS-F21607

(4.1) Rating

(2) Publication(s)

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

0.16 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

Pig FLT1 / VEGFR1 (Sandwich ELISA) ELISA Kit - LS-F22422

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Pig

Range:

0.31 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$627

Select

Sheep FLT1 / VEGFR1 (Sandwich ELISA) ELISA Kit - LS-F49030

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Sheep

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$911

Select

Pig FLT1 / VEGFR1 (Sandwich ELISA) ELISA Kit - LS-F6396

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Pig

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$929

Select

Human FLT1 / VEGFR1 (Sandwich ELISA) ELISA Kit - LS-F12942

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$441

Select

Human FLT1 / VEGFR1 (Sandwich ELISA) ELISA Kit - LS-F3685

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

1.638 - 400 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$588

Select

Human FLT1 / VEGFR1 (Sandwich ELISA) ELISA Kit - LS-F4997

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78.13 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Follicular Fluid, Plasma, Saliva, Serum, Tissue Homogenates

Price:

1 Plate/$610

Select

Rat FLT1 / VEGFR1 (Sandwich ELISA) ELISA Kit - LS-F12941

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$441

Select

Mouse FLT1 / VEGFR1 (CLIA) ELISA Kit - LS-F30765

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse

Range:

31.25 - 2000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

Select

Chicken FLT1 / VEGFR1 (Custom ELISA) ELISA Kit - LS-F13858

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Chicken

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$685

Select

Mouse FLT1 / VEGFR1 (Sandwich ELISA) ELISA Kit - LS-F28955

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

100 - 2500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

Select

Human FLT1 / VEGFR1 (CLIA) ELISA Kit - LS-F29725

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

Select

Human FLT1 / VEGFR1 (Sandwich ELISA) ELISA Kit - LS-F2571

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

156 - 10000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$636

Select

Mouse FLT1 / VEGFR1 (Sandwich ELISA) ELISA Kit - LS-F21392

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

Human FLT1 / VEGFR1 (Sandwich ELISA) ELISA Kit - LS-F24234

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

125 - 8000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$626

Select

Mouse FLT1 / VEGFR1 (Sandwich ELISA) ELISA Kit - LS-F39826

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

156 - 10000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Serum

Price:

1 Plate/$795

Select

Human FLT1 / VEGFR1 (Sandwich ELISA) ELISA Kit - LS-F24703

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

156 - 10000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$669

Select

Human FLT1 / VEGFR1 (CLIA) ELISA Kit - LS-F26063

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

27.43 - 20000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Cell Lysates, Follicular Fluid, Plasma, Saliva, Serum, Tissue Homogenates

Price:

1 Plate/$968

Select

Mouse FLT1 / VEGFR1 (CLIA) ELISA Kit - LS-F26066

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

27.43 - 20000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$990

Select

Human FLT1 / VEGFR1 (Sandwich ELISA) ELISA Kit - LS-F27313

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.5 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

Select

Rat FLT1 / VEGFR1 (Sandwich ELISA) ELISA Kit - LS-F27623

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.5 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

Select

Human FLT1 / VEGFR1 (Sandwich ELISA) ELISA Kit - LS-F36306

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

125 - 8000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Porcine FLT1 / VEGFR1 (Sandwich ELISA) ELISA Kit - LS-F56470

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Mouse FLT1 / VEGFR1 (Sandwich ELISA) ELISA Kit - LS-F56455

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Rat FLT1 / VEGFR1 (Sandwich ELISA) ELISA Kit - LS-F56488

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Viewing 1-25 of 38 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: ELISA Kits

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.