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Unfortunately, the antibody (ID:156042) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



FLT1 / VEGFR1

fms-related tyrosine kinase 1

Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. May play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. Can promote endothelial cell proliferation, survival and angiogenesis in adulthood. Its function in promoting cell proliferation seems to be cell-type specific. Promotes PGF-mediated proliferation of endothelial cells, proliferation of some types of cancer cells, but does not promote proliferation of normal fibroblasts (in vitro). Has very high affinity for VEGFA and relatively low protein kinase activity; may function as a negative regulator of VEGFA signaling by limiting the amount of free VEGFA and preventing its binding to KDR. Likewise, isoforms lacking a transmembrane domain, such as isoform 2, isoform 3 and isoform 4, may function as decoy receptors for VEGFA. Modulates KDR signaling by forming heterodimers with KDR. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate and the activation of protein kinase C. Mediates phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, leading to activation of phosphatidylinositol kinase and the downstream signaling pathway. Mediates activation of MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Phosphorylates SRC and YES1, and may also phosphorylate CBL. Isoform 1 phosphorylates PLCG. Promotes phosphorylation of AKT1 at 'Ser-473'. Promotes phosphorylation of PTK2/FAK1. Isoform 7 has a truncated kinase domain; it increases phosphorylation of SRC at 'Tyr-418' by unknown means and promotes tumor cell invasion.

Gene Name: fms-related tyrosine kinase 1
Family/Subfamily: Protein Kinase , VEGF Receptor
Synonyms: FLT1, FLT, FLT-1, Fms-related tyrosine kinase 1, SFlt1, VEGF-r1, VEG-R1, Tyrosine-protein kinase FRT, VEGFR-1, Fms-like tyrosine kinase 1, FRT, VEGF receptor 1, VEGFf-rI, VEGFR1
Target Sequences: NM_002019 NP_002010.2 P17948

Publications (1)

1
VEGFR-1 expressed by malignant melanoma-initiating cells is required for tumor growth. Frank NY, Schatton T, Kim S, Zhan Q, Wilson BJ, Ma J, Saab KR, Osherov V, Widlund HR, Gasser M, Waaga-Gasser AM, Kupper TS, Murphy GF, Frank MH. Cancer research. 2011 71:1474-85. (IHC) [PubMed:21212411] [PMC:PMC3083845]

Filtered By: None
Target
flt1-vegfr1 (154)
Reactivity
Human (115)
Mouse (33)
Rat (55)
Bat (4)
Chicken (1)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Guinea pig (4)
Horse (4)
Monkey (1)
Orangutan (3)
Pig (17)
Sheep (1)
Application
IHC (61)
IHC-Fr (3)
IHC-P (26)
WB (110)
Flo (15)
ELISA (40)
Func (2)
ICC (1)
IF (7)
IP (9)
Peptide-ELISA (5)
Host
rabbit (119)
mouse (33)
rat (1)
sheep (1)
Isotype
IgG (75)
IgG1 (16)
IgG1,k (15)
IgG2a (1)
Clonality
monoclonal mc (34)
polyclonal pc (120)
Clone
11G5 (1)
1453CT519.277.79 (1)
3D10 (1)
6D1/G11 (1)
7A6 (1)
8G6 (1)
EIC (1)
EWC (1)
EWF (1)
EWI (1)
FLT1/658 (2)
FLT1/659 (2)
FLT12 (1)
Flt-19 (1)
V12 (3)
VGR1T-1 (2)
Format
AP Conjugated (4)
APC (5)
APC Conjugated (9)
Azide-free (6)
Biotin Conjugated (13)
Cy3 Conjugated (5)
Cy7 Conjugated (5)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
FITC Conjugated (14)
HRP Conjugated (11)
Magnetic beads Conjugated (1)
PE Conjugated (10)
Sepharose Conjugated (1)
Unconjugated (78)
Epitope
C-Terminus (15)
N-Terminus (10)
aa27-329 (9)
aa167-424 (8)
aa18-308 (8)
aa19-146 (8)
aa303-524 (8)
Internal (4)
Extracellular Domain (3)
aa27-328 (3)
pTyr1048 (3)
pTyr1213 (3)
aa1251-1338 (2)
aa781-1338 (2)
pTyr1333 (2)
Tyr1327 (1)
aa1-250 (1)
aa1016-1065 (1)
aa1260-1340 (1)
aa1289-1338 (1)
aa1299-1317 (1)
aa27-758 (1)
aa278-298 (1)
aa279-299 (1)
aa31-35 (1)
aa980-1060 (1)
Publications
No (154)
Showing 1-25 out of 154 results
FLT1 / VEGFR1 Antibody (N-Terminus) IHC-plus™ LS-A9405
Anti-VEGFR1 antibody LS-A9405 IHC of human placenta, fetal capillary endothelial cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Rabbit Polyclonal to Human FLT1 / VEGFR1
Human
IHC IHC-P
Unconjugated
FLT1 / VEGFR1 Antibody (aa1251-1338) IHC-plus™ LS-B6701
Anti-VEGFR-1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6701 concentration 10 ug/ml.
Anti-VEGFR-1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6701 concentration 10 ug/ml.

Mouse Monoclonal (IgG1,k) to Human FLT1 / VEGFR1
Human
IHC IHC-P WB
Unconjugated
FLT1 / VEGFR1 Antibody (C-Terminus) IHC-plus™ LS-A9440
Anti-VEGFR1 antibody LS-A9440 IHC of human placenta, fetal capillary endothelial cells. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Rabbit Polyclonal to Human FLT1 / VEGFR1
Human
IHC IHC-P
Unconjugated
FLT1 / VEGFR1 Antibody (Extracellular Domain, clone Flt-19) LS-C58286

Mouse Monoclonal [clone Flt-19] (IgG) to Human FLT1 / VEGFR1
Human
ELISA IHC IHC-Fr IP
Unconjugated
FLT1 / VEGFR1 Antibody (aa1-250) LS-C6855

Mouse Monoclonal (IgG1) to Human FLT1 / VEGFR1
Mouse, Human
ELISA Flo WB
Unconjugated
FLT1 / VEGFR1 Antibody (Internal) IHC-plus™ LS-B7387
Anti-VEGFR-1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7387 concentration 5 ug/ml.

Rabbit Polyclonal (IgG) to Mouse FLT1 / VEGFR1
Mouse, Human
IHC IHC-P WB
Unconjugated
FLT1 / VEGFR1 Antibody LS-C160522
Formalin-fixed and paraffin-embedded human breast carcinoma reacted with VGFR1 Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Western blot of VGFR1 Antibody in MCF-7 cell line lysates (35 ug/lane). VGFR1 (arrow) was detected using the purified antibody.

Rabbit Polyclonal to Human FLT1 / VEGFR1
Human
Flo IHC IHC-P WB
Unconjugated
FLT1 / VEGFR1 Antibody (C-Terminus) LS-C40129

Rabbit Polyclonal (IgG) to Human FLT1 / VEGFR1
Human
ELISA WB
Unconjugated
FLT1 / VEGFR1 Antibody (aa303-524) LS-C296964

Rabbit Polyclonal (IgG) to Rat FLT1 / VEGFR1
Rat
IHC WB
Unconjugated
FLT1 / VEGFR1 Antibody (aa303-524, Biotin) LS-C300856

Rabbit Polyclonal (IgG) to Rat FLT1 / VEGFR1
Rat
IHC WB
Biotin Conjugated
FLT1 / VEGFR1 Antibody (aa18-308) LS-C374261
Western blot of FLT1 / VEGFR1 antibody.

Rabbit Polyclonal (IgG) to Rat FLT1 / VEGFR1
Rat
IHC WB
Unconjugated
FLT1 / VEGFR1 Antibody (clone V12) LS-C171014

Mouse Monoclonal [clone V12] (IgG1) to Human FLT1 / VEGFR1
Human
ICC IHC IHC-Fr WB
Unconjugated
FLT1 / VEGFR1 Antibody (clone V12, Sepharose) LS-C171293

Mouse Monoclonal [clone V12] (IgG1) to Human FLT1 / VEGFR1
Human
IP
Sepharose Conjugated
FLT1 / VEGFR1 Antibody (aa167-424, Biotin) LS-C299980
Western blot of recombinant FLKT1 / FLT-1 / VEGFR1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Rabbit Polyclonal (IgG) to Pig FLT1 / VEGFR1
Pig
WB
Biotin Conjugated
FLT1 / VEGFR1 Antibody (aa19-146, Biotin) LS-C299320
Western blot of recombinant FLKT1 / FLT-1 / VEGFR1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Rabbit Polyclonal (IgG) to Pig FLT1 / VEGFR1
Pig
WB
Biotin Conjugated
FLT1 / VEGFR1 Antibody (Extracellular Domain) LS-C124782

Mouse Monoclonal (IgG1) to Human FLT1 / VEGFR1
Human
ELISA IHC IHC-Fr IP
Unconjugated
FLT1 / VEGFR1 Antibody LS-C132866

Mouse Monoclonal (IgG1) to Human FLT1 / VEGFR1
Human
ELISA Flo WB
Unconjugated
FLT1 / VEGFR1 Antibody (aa1251-1338) IHC-plus™ LS-B8712
Anti-FLT1 / VEGFR1 antibody IHC staining of human prostate, endothelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
WB: HUVEC membrane cell lysate was probed with anti-Flt-1 (2g/ml).

Mouse Monoclonal (IgG1,k) to Human FLT1 / VEGFR1
Human
IHC IHC-P WB
Unconjugated
FLT1 / VEGFR1 Antibody (clone 3D10) LS-C109097
Western blot using FLT1 mouse monoclonal antibody against extracellular domain of human FLT1.

Mouse Monoclonal [clone 3D10] (IgG1) to Human FLT1 / VEGFR1
Human
ELISA WB
Unconjugated
FLT1 / VEGFR1 Antibody (Internal, DY650) LS-C141158

Rabbit Polyclonal to Human FLT1 / VEGFR1
Mouse, Rat, Human
Flo WB
DY650 Conjugated
FLT1 / VEGFR1 Antibody (Extracellular Domain, clone 6D1/G11) LS-C92347

Mouse Monoclonal [clone 6D1/G11] (IgG1) to Human FLT1 / VEGFR1
Human
ELISA
Unconjugated
FLT1 / VEGFR1 Antibody (aa18-308, FITC) LS-C421121
Western blot of FLT1 / VEGFR1 antibody.

Rabbit Polyclonal (IgG) to Rat FLT1 / VEGFR1
Rat
IHC WB
FITC Conjugated
FLT1 / VEGFR1 Antibody LS-C88676

Rabbit Polyclonal (IgG) to Human FLT1 / VEGFR1
Mouse, Rat, Human
WB
Unconjugated
FLT1 / VEGFR1 Antibody (C-Terminus) LS-C201759
Western blot of Human HepG2. FLT1 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Rabbit Polyclonal to Human FLT1 / VEGFR1
Dog, Guinea pig, Rat, Horse, Bat, Human
WB
Unconjugated
FLT1 / VEGFR1 Antibody (N-Terminus) IHC-plus™ LS-B9103
Anti-FLT1 / VEGFR1 antibody IHC staining of human small intestine, vessels. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Rabbit Polyclonal (IgG) to Human FLT1 / VEGFR1
Rat, Human
ELISA IHC IHC-P WB
Unconjugated

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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