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FLNB / TAP
filamin B, beta
Connects cell membrane constituents to the actin cytoskeleton. May promote orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Various interactions and localizations of isoforms affect myotube morphology and myogenesis. Isoform 6 accelerates muscle differentiation in vitro.
| Gene Name: | filamin B, beta |
| Synonyms: | FLNB, ABP-280, ABP-280 homolog, AOI, ABP-278, Actin binding protein 278, Actin-binding-like protein, Filamin homolog 1, FLN1L, FLN3, FH1, Filamin-3, LRS1, TAP, Thyroid autoantigen, Beta-filamin, Filamin B, beta, Filamin-B, FLN-B, TABP, Truncated ABP |
| Target Sequences: | NM_001457 NP_001448.2 O75369 |
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