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FLNA / Filamin A

filamin A, alpha

FLNA / Filamin A is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: filamin A, alpha
Synonyms: FLNA, ABPX, Actin binding protein 280, Actin-binding protein 280, Filamin A, FLN1, FMD, Filamin-A, Filamin-1, FLN, FLN-A, Non-muscle filamin, OPD1, OPD2, Alpha-filamin, NHBP, OPD, XMVD, CVD1, Filamin A, alpha, MNS, XLVD
Target Sequences: NM_001456 NP_001447.2 P21333

Publications (1)

1
Potential Utility of Protein Targets of Cysteine-S-Nitrosylation in Identifying Clinical Disease Status in Human Chagas Disease. Maria Paola Zago, John E Wiktorowicz, Heidi Spratt, Sue-Jie Koo, Natalia Barrientos, Aida Nuñez Burgos, Julio Nuñez Burgos, Facundo Iñiguez, Valentina Botelli, Ricardo Leon de la Fuente, Nisha Jain Garg. Frontiers in microbiology. 2019 January;9:3320. [Full Text Article] [PubMed:30697201] [PMC:PMC6340995]

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FLNA / Filamin A (15)
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Mouse (3)
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Guinea pig (1)
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12 x 8-Well Microstrips (1)
96-Well Microplate (1)
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Adherent Cell Cultures (1)
Cell Culture Supernatants (2)
Cell Lysates (3)
Plasma (8)
Serum (8)
Tissue Homogenates (4)
FLNA / Filamin A ELISA Kit
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Sandwich
96-Well Strip Plate
Human
1.88 - 120 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$834
FLNA / Filamin A ELISA Kit
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Sandwich
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
FLNA / Filamin A ELISA Kit
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Sandwich
12 x 8-Well Microstrips
Mouse
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
FLNA / Filamin A ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
FLNA / Filamin A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Guinea pig
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
FLNA / Filamin A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Porcine
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
FLNA / Filamin A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
FLNA / Filamin A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
FLNA / Filamin A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
FLNA / Filamin A ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
FLNA / Filamin A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
FLNA / Filamin A ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Human
3.76 - 240 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
500 Wells/$1,276; 1000 Wells/$1,903
FLNA / Filamin A ELISA Kit
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Custom
96-Well Strip Plate
Chicken
1 Plate/$929
FLNA / Filamin A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
18.75 - 1200 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$958
FLNA / Filamin A ELISA Kit
Select
Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$618
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).