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FKBP5 / FKBP51

FK506 binding protein 5

FKBP5 / FKBP51 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.

Gene Name: FK506 binding protein 5
Synonyms: FKBP5, 51 kd fk506-binding protein, 51 kDa FK506-binding protein, 51 kDa FK506-binding protein 5, 51 kDa FKBP, AIG6, Androgen-regulated protein 6, FKBP-51, FKBP-5, FKBP51, FF1 antigen, FK506 binding protein 5, p54, Ptg-10, Rotamase, T-cell FK506-binding protein, PPIase, PPIase FKBP5, FK506-binding protein 5, FKBP54, HSP90-binding immunophilin
Target Sequences: NM_004117 NP_004108.1 Q13451

Publications (1)

1
Regulation of Serine-Threonine Kinase Akt Activation by NAD+<sup>-Dependent Deacetylase SIRT7. Yu J, Qin B, Wu F, Qin S, Nowsheen S, Shan S, Zayas J, Pei H, Lou Z, Wang L. Cell reports. 2017 January;18:1229-1240. [Full Text Article] [PubMed:28147277] [PMC:PMC5298804]

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Products
Proteins (13)
Over-Expression Lysate (8)
Recombinant (5)
FKBP5 / FKBP51 (13)
No (12)
Yes (1)
GST, N-terminus (1)
His (1)
His, N-Terminal (1)
His-GST (1)
Myc-DDK (Flag) (9)
Human (8)
Mouse (1)
293T Cells (4)
E. coli (3)
HEK 293 Cells (5)
Wheat Germ Extract (1)
Purified (1)
FKBP5 / FKBP51 Protein - 12.5% SDS-PAGE of human FKBP5 stained with Coomassie Blue
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Wheat Germ Extract
GST, N-terminus
76.01 kDa
10 µg/$479; 25 µg/$670
FKBP5 / FKBP51 Protein - Recombinant FK506 Binding Protein 5 By SDS-PAGE
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E. coli
His
52.4 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
FKBP5 / FKBP51 Protein - Purified recombinant protein FKBP5 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
51 kDa
20 µg/$1,107
FKBP5 / FKBP51 Protein - Recombinant FK506 Binding Protein 5 By SDS-PAGE
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E. coli
His-GST
78.1 kDa
10 µg/$285; 50 µg/$470; 100 µg/$750; 200 µg/$937; 1 mg/$2,063; 500 µg/$1,594; 5 mg/$3,277; 2 mg/$2,252
FKBP5 / FKBP51 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
51 kDa
100 µg/$494
FKBP5 / FKBP51 Protein
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E. coli
His, N-Terminal
51 kDa
50 µg/$419
FKBP5 / FKBP51 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
29.9 kDa
100 µg/$494
FKBP5 / FKBP51 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
51 kDa
100 µg/$494
FKBP5 / FKBP51 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
51 kDa
100 µg/$494
FKBP5 / FKBP51 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
51 kDa
20 µg/$150
FKBP5 / FKBP51 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
51 kDa
20 µg/$150
FKBP5 / FKBP51 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
51 kDa
20 µg/$150
FKBP5 / FKBP51 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
29.9 kDa
20 µg/$150
Viewing 1-13 of 13 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).