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20700 44th Avenue W
Lynnwood, WA 98036
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FKBP5 / FKBP51
FK506 binding protein 5
FKBP5 / FKBP51 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.
| Gene Name: | FK506 binding protein 5 |
| Synonyms: | FKBP5, 51 kd fk506-binding protein, 51 kDa FK506-binding protein, 51 kDa FK506-binding protein 5, 51 kDa FKBP, AIG6, Androgen-regulated protein 6, FKBP-51, FKBP-5, FKBP51, FF1 antigen, FK506 binding protein 5, p54, Ptg-10, Rotamase, T-cell FK506-binding protein, PPIase, PPIase FKBP5, FK506-binding protein 5, FKBP54, HSP90-binding immunophilin |
| Target Sequences: | NM_004117 NP_004108.1 Q13451 |
Publications (1)
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